Immuno-gold localization of Pfhsp and Pfgrp. A. Sections of a mature segmenter with rappit antiserum against Pfhsp fusion protein and protein A-gold. The nuclei (N) of budding merozoites (m) are labeled diffusely with colloidal gold particles (arrows). B. Section of mature gametocyte incubated witrh antiserum against Pfgrp peptide and protein A-gold.. Label (arrows) is associated with membranes of the ER. C. Sections of a schizont. Lable (arrows) is associated with discrete areas of the schizont cytoplasm that correspond to ER. Not absence of label on the nucleus (N) and parasitophorous vacuole (PV). Bar – 0.5 mm.

Kumar N, Koski G, Harada M, Aikawa M, Zheng H. Induction and localization of Plasmodium falciparum stress proteins related to the heat shock protein 70 family. Mol Biochem Parasitol. 1991 48:47-58. Copyright Elsevier 2009.