Localisation of SBP1 C-terminal mutants. Immunofluorescence analysis of RBCs infected with either normal (3D7) or transgenic parasites expressing a chimeric SBP1 protein in which the C-terminal domain of SBP1 was replaced with the C-terminal domain of P. falciparum AMA1 (SBP1–AMA1-C). Chimeras localised this protein correctly to Murer’s Clefts.
Kats LM, Proellocks NI, Buckingham DW, Blanc L, Hale J, Guo X, Pei X, Herrmann S, Hanssen EG, Coppel RL, Mohandas N, An X, Cooke BM. Interactions between Plasmodium falciparum skeleton-binding protein 1 and the membrane skeleton of malaria-infected red blood cells. Biochim Biophys Acta. 2015 1848(7):1619-1628.
PubMed Article: Interactions between Plasmodium falciparum skeleton-binding protein 1 and the membrane skeleton of malaria-infected red blood cells
Other associated proteins
PFID | Formal Annotation |
---|---|
PF3D7_1133400 | apical membrane antigen 1 |