Rep20 DNA-FISH in WT 3D7C8, PfRecQ1ΔD3, and PfWRNΔ. Rep20 probe was labeled with Biotin and then incubated with streptavidin (Alexa Fluor 568 conjugate, Thermo Fisher, red); chromosomal DNA was stained with DAPI (blue), representing the nuclear area. Parasites synchronized at ring stage were used for this DNA-FISH. Resolution of A is 600 dpi.

Li Z, Yin S, Sun M, Cheng X, Wei J, Gilbert N, Miao J, Cui L, Huang Z, Dai X, Jiang L. DNA helicase RecQ1 regulates mutually exclusive expression of virulence genes in via heterochromatin alteration. Proc Natl Acad Sci Plasmodium falciparum U S A. 2019 116(8):3177-3182. PMID: 30728298.