Localization of AP-2μ-3xHA and Rab5B by immunoelectron microscopy. Electron micrographs of vesicular colocalization of AP-2μ-3xHA (18 nm gold particles) and Rab5B (12 nm gold particles) in developing trophozoites. N, nucleus; ER, endoplasmic reticulum; H, hemozoin; black arrowhead, vesicles colabeled for both proteins. At least some cytosolic AP-2μ-positive vesicles also contained Rab5B, an effector of endosome-like transport between the plasma membrane and the
FV.
Henrici RC, Edwards RL, Zoltner M, van Schalkwyk DA, Hart MN, Mohring F, Moon RW, Nofal SD, Patel A, Flueck C, Baker DA, Odom John AR, Field MC, Sutherland CJ. The Plasmodium falciparum Artemisinin Susceptibility-Associated AP-2 Adaptin μ Subunit is Clathrin Independent and Essential for Schizont Maturation. mBio. 2020 Feb 25;11(1). pii: e02918-19.
Other associated proteins
PFID | Formal Annotation |
---|---|
PF3D7_1218300 | AP-2 complex subunit mu |