Redox-proteome changes induced by chloroquine across the intraerythrocytic stages of P. falciparum Dd2
Radfar A, Diez A, Bautista JM. Chloroquine mediates specific proteome oxidative damage across the erythrocytic cycle of resistant Plasmodium falciparum. Free Radic Biol Med. 2008 44(12):2034-42. PMID: 18397762.
Fold Change
PFID Old Annotation Ring Troph Schiz EC# Transcript
PF3D7_1150400 erythrocyte membrane protein 1, PfEMP1 0.03 n/d 76.50
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PF3D7_0922500
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phosphoglycerate kinase 0.14 n/d 13.80 2.7.2.3
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PF3D7_0413600
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26S protease regulatory subunit 6B, putative; 26S proteasome AAA-ATPase subunit RPT3 0.52 n/d 17.17 3.6.4.8
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PF3D7_1219000
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formin 2 0.52 n/d 3.86
PF3D7_0203000
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repetitive organellar protein, putative 1.24 n/d 0.92
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PF3D7_1347500
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DNA/RNA-binding protein Alba 4 n/d n/d n/d
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PF3D7_1202400
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peptidyl-prolyl cis-trans isomerase n/d n/d n/d 5.2.1.8
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PF3D7_1330600
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elongation factor Tu, putative n/d n/d 1.62
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PF3D7_0619400
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cell division cycle protein 48 homologue, putative 0.22 23.00 11.20
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PF3D7_0104200
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StAR-related lipid transfer protein 0.88 8.25 1.66
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PF3D7_0917900
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heat shock protein 70 0.23 5.45 5.08
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PF3D7_1200600
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erythrocyte membrane protein 1, PfEMP1 n/d 3.62 n/d
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PF3D7_1124700
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GrpE protein homolog, mitochondrial, putative n/d 2.95 n/d
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PF3D7_0827900
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protein disulfide isomerase 0.13 2.91 22.00 5.3.4.1
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PF3D7_0818900
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heat shock protein 70 n/d 2.15 n/d
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PF3D7_1117700
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GTP-binding nuclear protein RAN/TC4 0.36 1.76 55.50
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PF3D7_1443900
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heat shock protein 90, putative 0.06 1.67 50.50
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PF3D7_0708400
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heat shock protein 90 0.14 1.67 13.33
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PF3D7_1311800
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M1-family alanyl aminopeptidase n/d 1.41 1.83 3.4.11.2
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PF3D7_1454400
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aminopeptidase P 0.16 1.35 52.29 3.4.11.9
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PF3D7_1134000
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heat shock protein 70 0.53 1.04 3.00
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PF3D7_1239800
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conserved Plasmodium protein, unknown function 0.54 1.03 5.19
PF3D7_0603900 conserved Plasmodium protein, unknown function 1.82 1.03 0.63
PF3D7_1015600
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heat shock protein 60 0.43 0.89 4.02
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PF3D7_1404900
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conserved Plasmodium protein, unknown function n/d 0.78 n/d
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PF3D7_1311800
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M1-family alanyl aminopeptidase 0.25 0.71 2.17 3.4.11.2
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PF3D7_1015600
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heat shock protein 60 0.13 0.59 18.18
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PF3D7_0803800
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proteasome subunit beta type-4 n/d 0.50 n/d 3.4.25.1
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PF3D7_1015600
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heat shock protein 60 0.74 0.50 2.99
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PF3D7_0917900
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heat shock protein 70 n/d 0.14 n/d
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PF3D7_1015900
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enolase n/d 0.13 n/d 4.2.1.11
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