Redox-proteome changes induced by chloroquine across the intraerythrocytic stages of P. falciparum Dd2
Radfar A, Diez A, Bautista JM. Chloroquine mediates specific proteome oxidative damage across the erythrocytic cycle of resistant Plasmodium falciparum. Free Radic Biol Med. 2008 44(12):2034-42. PMID: 18397762.
Fold Change
PFID Old Annotation Ring Troph Schiz EC# Transcript
PF11_0521 Erythrocyte membrane protein 1 0.03 n/d 76.50
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PFI1105w
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Phosphoglycerate kinase 0.14 n/d 13.80 2.7.2.3
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PFD0665c
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26S Proteasome aaa-ATPase subunit Rpt3, putative 0.52 n/d 17.17 3.6.4.8
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PFL0925w
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Formin 2, putative 0.52 n/d 3.86
PFB0145c
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Hypothetical protein 1.24 n/d 0.92
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MAL13P1.237
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Hypothetical protein n/d n/d n/d
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PFL0120c
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Cyclophilin, putative n/d n/d n/d 5.2.1.8
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MAL13P1.164
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Elongation factor tu, putative n/d n/d 1.62
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PFF0940c
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Cell division cycle protein 48 homologue, putative 0.22 23.00 11.20
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PFA0210c
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Hypothetical protein 0.88 8.25 1.66
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PFI0875w
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HSP 0.23 5.45 5.08
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PFL0030c
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Erythrocyte membrane protein 1 n/d 3.62 n/d
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PF11_0258
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Co-chaperone GrpE, putative n/d 2.95 n/d
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MAL8P1.17
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Disulphide isomerase precursor, putative 0.13 2.91 22.00 5.3.4.1
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PF08_0054
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HSP70 n/d 2.15 n/d
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PF11_0183
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GTP-binding nuclear protein ran/tc4 0.36 1.76 55.50
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PF14_0417
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HSP, putative 0.06 1.67 50.50
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PF07_0029
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HSP 86 0.14 1.67 13.33
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MAL13P1.56
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M1-family aminopeptidase n/d 1.41 1.83 3.4.11.2
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PF14_0517
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Peptidase, putative 0.16 1.35 52.29 3.4.11.9
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PF11_0351
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HSP hsp70 homologue 0.53 1.04 3.00
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PFL1930w
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Hypothetical protein 0.54 1.03 5.19
PFF0190c Hypothetical protein 1.82 1.03 0.63
PF10_0153
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HSP60 0.43 0.89 4.02
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PF14_0046
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Hypothetical protein n/d 0.78 n/d
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MAL13P1.56
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M1-family aminopeptidase 0.25 0.71 2.17 3.4.11.2
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PF10_0153
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HSP60 0.13 0.59 18.18
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MAL8P1.142
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proteasome subunit beta type-4 n/d 0.50 n/d 3.4.25.1
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PF10_0153
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HSP60 0.74 0.50 2.99
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PFI0875w
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HSP n/d 0.14 n/d
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PF10_0155
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Enolase n/d 0.13 n/d 4.2.1.11
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