Genes whose expression is highly positively or negatively correlated with pfcrt or pfmdr1
Adjalley SH, Scanfeld D, Kozlowski E, Llinás M, Fidock DA. Genome-wide transcriptome profiling reveals functional networks involving the Plasmodium falciparum drug resistance transporters PfCRT and PfMDR1.
$ Genes whose expression is highly correlated to that of both pfcrt and pfmdr1
Gene ID Previous Gene ID Annotation #E.C Transcript
DNA/RNA metabolism PF3D7_0215700 PFB0715w DNA-directed RNA polymerase II second largest subunit, putative 2.7.7.6
Image left : 32px, top : 4px
PF3D7_0422500 PFD1060w pre-mRNA-splicing helicase BRR2, putative (BRR2) 3.6.4.13
Image left : 32px, top : 4px
PF3D7_0513300 PFE0660c
Image left : 8px, top : 12px
purine nucleoside phosphorylase 2.4.2.1
Image left : 32px, top : 4px
PF3D7_0623900 PFF1150w ribonuclease H2 subunit A, putative 3.1.26.4
Image left : 32px, top : 4px
PF3D7_1126900 PF11_0280 small nuclear ribonucleoprotein F, putative
PF3D7_1421400 PF14_0207 DNA-directed RNA polymerase III subunit C, putative 2.7.7.6
Image left : 32px, top : 4px
PF3D7_1427800 PF14_0256 exosome complex exonuclease rrp41, putative 3.1.13.1
Image left : 32px, top : 4px
Translation PF3D7_1126000 PF11_0270
Image left : 8px, top : 12px
Image left : 8px, top : 12px
threonine--tRNA ligase (ThrRS) 6.1.1.3
Image left : 32px, top : 4px
PF3D7_1130200 PF11_0313
Image left : 8px, top : 12px
Image left : 8px, top : 12px
60S ribosomal protein P0
Image left : 32px, top : 4px
PF3D7_1332800 PF13_0178 translation initiation factor 6, putative
Image left : 32px, top : 4px
PF3D7_1367700 PF13_0354
Image left : 8px, top : 12px
alanine--tRNA ligase (AlaRS) 6.1.1.7
Image left : 32px, top : 4px
PF3D7_1445100 PF14_0428 histidine--tRNA ligase, putative 6.1.1.21
Image left : 32px, top : 4px
PF3D7_1204300 PFL0210c
Image left : 8px, top : 12px
eukaryotic translation initiation factor 5A (EIF5A)
Image left : 32px, top : 4px
PF3D7_1445300 PF14_0430 mitochondrial ribosomal protein S29 precursor, putative
Image left : 32px, top : 4px
PF3D7_0819100 PF08_0053 BRIX domain, putative (ribosomal RNA processing)
PF3D7_0729400 PF07_0122 Ribosome biogenesis protein BRX1 homolog, putative
Image left : 32px, top : 4px
Redox PF3D7_0717900 MAL7P1.88
Image left : 8px, top : 12px
thioredoxin-like protein
Image left : 32px, top : 4px
PF3D7_0729200 MAL7P1.159
Image left : 8px, top : 12px
Image left : 8px, top : 12px
1-cys peroxiredoxin 1.11.1.15
Image left : 32px, top : 4px
PF3D7_0923800 PFI1170c
Image left : 8px, top : 12px
Image left : 8px, top : 12px
thioredoxin reductase 1.8.1.9
Image left : 32px, top : 4px
PF3D7_1438900 PF14_0368
Image left : 8px, top : 12px
thioredoxin peroxidase 1 (Trx-Px1) 1.11.1.15
Image left : 32px, top : 4px
Metabolic enzymes PF3D7_0310300 PFC0430w phosphoglycerate mutase, putative 5.4.2.11
Image left : 32px, top : 4px
PF3D7_1015900 PF10_0155
Image left : 8px, top : 12px
Image left : 8px, top : 12px
enolase 4.2.1.11
Image left : 32px, top : 4px
PF3D7_1033400 PF10_0325
Image left : 8px, top : 12px
Image left : 8px, top : 12px
haloacid dehalogenase-like hydrolase, putative 3.8.1.-
Image left : 32px, top : 4px
PF3D7_1324900 PF13_0141
Image left : 8px, top : 12px
Image left : 8px, top : 12px
L-lactate dehydrogenase 1.1.1.27
Image left : 32px, top : 4px
PF3D7_1469600 PF14_0664
Image left : 8px, top : 12px
Image left : 8px, top : 12px
biotin carboxylase subunit of acetyl CoA carboxylase, putative 6.3.4.14
Image left : 32px, top : 4px
PF3D7_1012400 PF10_0121
Image left : 8px, top : 12px
Image left : 8px, top : 12px
hypoxanthine-guanine phosphoribosyltransferase (HGPRT) 2.4.2.8
Image left : 32px, top : 4px
Protein Modifications/Processing PF3D7_0213400 PFB0605w
Image left : 8px, top : 12px
Image left : 8px, top : 12px
protein kinase 7 2.7.11.1
Image left : 32px, top : 4px
PF3D7_1114700 PF11_0156
Image left : 8px, top : 12px
Image left : 8px, top : 12px
serine/threonine protein kinase 2.7.11.1
Image left : 32px, top : 4px
PF3D7_1201600 PFL0080c NIMA related kinase 3 2.7.11.1
Image left : 32px, top : 4px
PF3D7_0923100 PFI1135c OTU-like cysteine protease, putative 3.4.22.-
Image left : 32px, top : 4px
Protein Folding/Trafficking PF3D7_0418200 PFD0880w golgi organization and biogenesis factor, putative
Image left : 32px, top : 4px
PF3D7_0823800 PF08_0032 DnaJ protein, putative
Image left : 32px, top : 4px
PF3D7_1307200 PF13_0036 DnaJ protein, putative
Image left : 32px, top : 4px
PF3D7_1250500 PFL2425w adaptor-related protein complex 3, sigma 2 subunit, putative
PF3D7_0606700 PFF0330w coatomer alpha subunit, putative
Image left : 32px, top : 4px
PF3D7_0718000 MAL7P1.89
Image left : 8px, top : 12px
dynein heavy chain, putative
Image left : 32px, top : 4px
PF3D7_0903100 PFI0150c retrieval receptor for endoplasmic reticulum membrane proteins, putative
Image left : 32px, top : 4px
Transporters/Components of the digestive vacuole PF3D7_0103200 PFA0160c nucleoside transporter, putative
Image left : 32px, top : 4px
PF3D7_0418500 PFD0895c Bet3 transport protein, putative
Image left : 32px, top : 4px
PF3D7_0519200 PFE0965c vacuolar ATP synthetase 3.6.3.14
Image left : 32px, top : 4px
PF3D7_0523000 PFE1150w
Image left : 8px, top : 12px
Image left : 8px, top : 12px
multidrug resistance protein 3.6.3.44
Image left : 32px, top : 4px
PF3D7_0614300 PFF0690c organic anion transporter
Image left : 32px, top : 4px
PF3D7_0709000 MAL7P1.27
Image left : 8px, top : 12px
Image left : 8px, top : 12px
chloroquine resistance transporter
Image left : 32px, top : 4px
PF3D7_0810200 PF08_0098 ABC1 family, putative (ABCK1)
Image left : 32px, top : 4px
PF3D7_1037300 PF10_0366
Image left : 8px, top : 12px
Image left : 8px, top : 12px
ADP/ATP transporter on adenylate translocase
Image left : 32px, top : 4px
PF3D7_1132500 PF11_0334 amino acid transporter, putative
Image left : 32px, top : 4px
PF3D7_1347200 PF13_0252
Image left : 8px, top : 12px
Image left : 8px, top : 12px
nucleoside transporter 1
Image left : 32px, top : 4px
PF3D7_1354400 MAL13P1.271 V-type ATPase, putative 3.6.3.14
Image left : 32px, top : 4px
PF3D7_1434000 PF14_0321
Image left : 8px, top : 12px
CCR4-associated factor 16, putative (CAF16)
Image left : 32px, top : 4px
PF3D7_1456800 PF14_0541
Image left : 8px, top : 12px
V-type H( )-translocating pyrophosphatase, putative 3.6.1.1
Image left : 32px, top : 4px
PF3D7_1129900 PF11_0310 transporter, putative
Image left : 32px, top : 4px
PF3D7_0617000 PFF0825c mitochondrial import receptor subunit tom40, putative
PF3D7_1454400 PF14_0517
Image left : 8px, top : 12px
Image left : 8px, top : 12px
aminopeptidase P 3.4.11.9
Image left : 32px, top : 4px
PF3D7_1471100 PF14_0678
Image left : 8px, top : 12px
exported protein 2
Image left : 32px, top : 4px
Genes whose expression is highly anti-correlated to that of both pfcrt and pfmdr1
Gene ID Previous Gene ID Annotation
DNA/RNA metabolism PF3D7_0720100 PF07_0083 small subunit rRNA processing protein, putative
Image left : 32px, top : 4px
PF3D7_1407300 PF14_0070 pre-mRNA splicing factor, putative
Image left : 32px, top : 4px
PF3D7_0409100 PFD0450c pre-mRNA splicing factor, putative
Image left : 32px, top : 4px
PF3D7_0524900 PFE1240w S-adenosyl-l-methionine-dependent tRNA 4-demethylwyosine synthase, putative
Image left : 32px, top : 4px
PF3D7_0610100 PFF0500c step II splicing factor, putative
Image left : 32px, top : 4px
PF3D7_1207100 PFL0355c small subunit rRNA processing factor, putative
Image left : 32px, top : 4px
PF3D7_1302600 PF13_0013
Image left : 8px, top : 12px
deoxyhypusine hydroxylase 1.14.99.29
Image left : 32px, top : 4px
PF3D7_1125300 PF11_0264
Image left : 8px, top : 12px
DNA-dependent RNA polymerase 2.7.7.6
Image left : 32px, top : 4px
PF3D7_1307600 PF13_0040
Image left : 8px, top : 12px
DNA-directed RNA polymerase alpha chain, putative 2.7.7.6
Image left : 32px, top : 4px
PF3D7_1450300 PF14_0478
Image left : 8px, top : 12px
DNA polymerase delta interacting protein, putative
Image left : 32px, top : 4px
PF3D7_0807100 PF08_0111
Image left : 8px, top : 12px
RNA helicase, putative 3.6.4.13
Image left : 32px, top : 4px
PF3D7_1021500 PF10_0209 RNA helicase, putative 3.6.4.13
Image left : 32px, top : 4px
PF3D7_0105900 PFA0290w DNA binding protein, putative 3.1.11.1
Image left : 32px, top : 4px
PF3D7_0610900 PFF0535c trancription factor, putative
Image left : 32px, top : 4px
PF3D7_0611400 PFF0560c
Image left : 8px, top : 12px
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin
Image left : 32px, top : 4px
PF3D7_0617800 PFF0860c
Image left : 8px, top : 12px
histone H2A
Image left : 32px, top : 4px
PF3D7_0623600 PFF1135w transcription or splicing factor-like protein, putative
Image left : 32px, top : 4px
PF3D7_0508700 PFE0430w ATP-dependent RNA helicase, putative 3.6.4.13
Image left : 32px, top : 4px
PF3D7_1033600 PF10_0327 pre-mRNA-splicing factor cef1, putative
Image left : 32px, top : 4px
PF3D7_1422800 PF14_0218 actin-related protein homolog, arp4 homolog
Image left : 32px, top : 4px
PF3D7_0111500 PFA0555c
Image left : 8px, top : 12px
UMP-CMP kinase, putative (nucleic acid synthesis) 2.7.4.14
Image left : 32px, top : 4px
Translation PF3D7_0716800 MAL7P1.81 eukaryotic translation initiation factor 3 37.28 kDa subunit, putative
Image left : 32px, top : 4px
PF3D7_0716100 PF07_0067 large ribosomal subunit assembling factor, putative
Image left : 32px, top : 4px
PF3D7_0416100 PFD0780w
Image left : 8px, top : 12px
Image left : 8px, top : 12px
glutamyl-tRNA(Gln) amidotransferase subunit A, putative 6.3.5.7
Image left : 32px, top : 4px
PF3D7_0420400 PFD0990w
Image left : 8px, top : 12px
Image left : 8px, top : 12px
ribosome recycling factor, putative
Image left : 32px, top : 4px
PF3D7_0309700 PFC0405c ribosomal protein l7ae, putative
Image left : 32px, top : 4px
PF3D7_1446900 PF14_0447 glutaminyl-peptide cyclotransferase, putative 2.3.2.5
Image left : 32px, top : 4px
Protein Catabolism PF3D7_1017900 PF10_0174 26s proteasome regulatory subunit p55, putative 3.4.25.1
Image left : 32px, top : 4px
PF3D7_0815700 PF08_0067
Image left : 8px, top : 12px
ubiquitin
Image left : 32px, top : 4px
PF3D7_1317000 PF13_0096 ubiquitin carboxyl-terminal hydrolase, putative
Image left : 32px, top : 4px
PF3D7_0904600 PFI0225w ubiquitin specific protease, putative 3.4.19.12
Image left : 32px, top : 4px
PF3D7_0413900 PFD0680c ubiquitin carboxyl-terminal hydrolase a, putative 3.4.19.12
Image left : 32px, top : 4px
PF3D7_0413600 PFD0665c
Image left : 8px, top : 12px
26S protease regulatory subunit 6B, putative; 26S proteasome AAA-ATPase subunit RPT3 3.6.4.8
Image left : 32px, top : 4px
PF3D7_0314000 PFC0581w co-chaperone p23
Image left : 32px, top : 4px
Transporters PF3D7_1303500 PF13_0019
Image left : 8px, top : 12px
sodium/hydrogen exchanger, Na , H antiporter
Image left : 32px, top : 4px
PF3D7_1352100 PF13_0271 ABC transporter, (heavy metal transporter family), putative
Image left : 32px, top : 4px
Metabolic Enzymes PF3D7_0614000 PFF0680c thiamine-phosphate synthase, putative 2.5.1.3
Image left : 32px, top : 4px
PF3D7_1139700 PF11_0407 adrenodoxin reductase, putative (electron transfer) 1.18.1.2
Image left : 32px, top : 4px
PF3D7_0413500 PFD0660w phosphoglycerate mutase, putative (glycolysis) 5.4.2.2
Image left : 32px, top : 4px
PF3D7_1320800 PF13_0121
Image left : 8px, top : 12px
dihydrolipamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex (TCA cycle) 2.3.1.61
Image left : 32px, top : 4px
PF3D7_0934700 PFI1680w UBX domain, putative (regulator of AAA ATPases)
Image left : 32px, top : 4px
Kinases PF3D7_1121900 PF11_0227 serine/threonine protein kinase, putative 2.7.11.1
Image left : 32px, top : 4px
PF3D7_1123100 PF11_0242
Image left : 8px, top : 12px
Image left : 8px, top : 12px
calcium-dependent protein kinase 7 2.7.11.17
Image left : 32px, top : 4px
PF3D7_1414500 PF14_0143
Image left : 8px, top : 12px
atypical protein kinase, ABC-1 family, putative 1.14.13.-
Image left : 32px, top : 4px
PF3D7_0111500 PFA0555c
Image left : 8px, top : 12px
UMP-CMP kinase, putative (nucleic acid synthesis) 2.7.4.14
Image left : 32px, top : 4px
Cell-related functions PF3D7_1470600 PF14_0673 RAP protein, putative (GTPases)
Image left : 32px, top : 4px
PF3D7_1220300 PFL0975w Cell cycle associated protein, putative
Image left : 32px, top : 4px
PF3D7_0806600 MAL8P1.132 kinesin-like protein, putative
Image left : 32px, top : 4px
Unknown Function PF3D7_1252200 PFL2510w chitinase 3.2.1.14
Image left : 32px, top : 4px
PF3D7_0813200 MAL8P1.96 CS domain protein, putative
Image left : 32px, top : 4px
PF3D7_1033500 PF10_0326 WD-repeat protein, putative
Image left : 32px, top : 4px
PF3D7_1123200 PF11_0243 leucine-rich repeat protein
Image left : 32px, top : 4px
PF3D7_0921600 PFI1060w tetratricopeptide repeat family protein, putative
Image left : 32px, top : 4px
PF3D7_1309400 PF13_0050 HORMA domain protein, putative
Image left : 32px, top : 4px
PF3D7_1344100 MAL13P1.395 krox-like protein, putative
Image left : 32px, top : 4px
Online articles related to Genes whose expression is highly positively or negatively correlated with pfcrt or pfmdr1 retrieved from PubMed