Effect of hyperoxia on gene expression
Torrentino-Madamet M, Alméras L, Desplans J, Le Priol Y, Belghazi M, Pophillat M, Fourquet P, Jammes Y, Parzy D. Global response of Plasmodium falciparum to hyperoxia: a combined transcriptomic and proteomic approach. Malar J. 2011 Jan 11;10:4. PMID: 21223545;
PfID Annotation % change EC Transcript Functional category
33361 PF3D7_1230200 vacuolar transporter chaperone, putative, pseudogene 35.98 2.7.1.151 Intracellular traffic
33355 PF3D7_1210900 GPI mannosyltransferase I 31.66 2.4.1.83
Lipid metabolism
33285 PF3D7_0308000 DNA polymerase delta small subunit, putative 31.33 2.7.7.7
DNA metabolism
33311 PF3D7_0725000 exonuclease I, putative 26.88 3.1.16.1
DNA metabolism
33328 PF3D7_1004400 RNA-binding protein, putative 26.80
RNA metabolism
33339 PF3D7_1034600
translation initiation factor IF-3, putative 24.11
Translation
33286 PF3D7_0311600 dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit ost1, putative 22.35 2.4.99.18
Lipid metabolism
PF07_0131 22.19 Protein export
33343 PF3D7_1111100 replication factor C subunit 5, putative 21.73
DNA metabolism
33337 PF3D7_1028400
ribosome biogenesis protein rpf2, putative 21.36
Translation
33308 PF3D7_0715600 GTP-binding translation elongation factor tu family protein, putative 21.07
Translation
33372 PF3D7_1309400 HORMA domain protein, putative 20.93
Chromosome structure
33404 PF3D7_1435700 ataxin-2 like protein, putative 20.35
Post translational modification
33296 PF3D7_0504000 cation transporting P-ATPase, ATPase3 17.36 3.6.3.12
Transport
33353 PF3D7_1206500 Tat binding protein 1(TBP-1)-interacting protein, putative 17.17
Post translational modification
33306 PF3D7_0708800
heat shock protein 110 17.08
Post translational modification
33344 PF3D7_1122900
dynein heavy chain, putative 16.71
Invasion and motility
33351 PF3D7_1201400 Plasmodium exported protein, unknown function 16.48
Protein export
33303 PF3D7_0628800
glutamyl-tRNA(Gln) amidotransferase subunit B, putative 16.43 6.3.5.7
Translation
33312 PF3D7_0730100 tRNA pseudouridine synthase D, putative 16.41 5.4.99.12
RNA metabolism
33304 PF3D7_0628900 RAP protein, putative 15.30
Unknown function
33406 PF3D7_1437900
HSP40, subfamily A 15.26
Post translational modification
33936 PF3D7_1249900 ribosomal RNA small subunit methyltransferase a2, putative 14.97
Organellar functions
33402 PF3D7_1431800
apyrase 14.44 3.6.1.5
Nucleotide metabolism
33309 PF3D7_0719200
NIMA related kinase 4 14.04 2.7.11.1
Post translational modification
33398 PF3D7_1411400
plastid replication-repair enzyme 14.02 2.7.7.7
Organellar functions
33301 PF3D7_0607800 GTP-binding protein, putative 13.83
Intracellular traffic
33380 PF3D7_1334300
MSP7-like protein 13.68
Invasion and motility
33379 PF3D7_1330800 RNA-binding protein, putative 13.37
RNA metabolism
33280 PF3D7_0212000 GDP-fructose:GMP antiporter, putative 12.90
Transport
33407 PF3D7_1443400
WD repeat-containing protein, putative 12.35
Unknown function
33274 PF3D7_0111400 conserved Plasmodium protein, unknown function gametocyte exported protein 19 12.28 Protein export
33396 PF3D7_1405400 DNA mismatch repair protein, putative 12.27
DNA metabolism
33325 PF3D7_0930200 leucine-rich repeat protein 12.17
Unknown function
33403 PF3D7_1434300
Hsp70/Hsp90 organizing protein 12.07
Post translational modification
33302 PF3D7_0612300 transmembrane protein 234, putative 12.00 Unknown function
33371 PF3D7_1307300 ATP-dependent RNA helicase dbp6 11.62 3.6.4.13
RNA metabolism
33376 PF3D7_1319100 ubiquitin carboxyl-terminal hydrolase mindy, putative 11.36 3.4.19.12
Post translational modification
33340 PF3D7_1035000 U2 snRNA/tRNA pseudouridine synthase, putative 11.24 5.4.99.12
RNA metabolism
33400 PF3D7_1416200
metacaspase-3, putative 11.10
Post translational modification
33324 PF3D7_0928800 serine/threonine protein kinase, putative 10.65 2.7.11.1
Post translational modification
33299 PF3D7_0524800 ubiquitin fusion degradation protein 1, putative 10.46
Post translational modification
33374 PF3D7_1313400 DEAD box helicase, putative 10.36 3.6.1.3
DNA metabolism
33384 PF3D7_1351600 glycerol kinase 10.25 2.7.1.30
Carbohydrate metabolism
33334 PF3D7_1020800
dihydrolipoamide acyltransferase component E2 10.12 2.3.1.12
Organellar functions
33287 PF3D7_0316300 inorganic pyrophosphatase 10.06 3.6.1.1
Lipid metabolism
33364 PF3D7_1241700 replication factor C subunit 4, putative 9.94
DNA metabolism
33289 PF3D7_0413900 ubiquitin carboxyl-terminal hydrolase 13, putative 9.93 3.4.19.12
Post translational modification
33357 PF3D7_1221400 inner membrane complex protein 1h, putative 9.77
Invasion and motility
33392 PF3D7_1360500 guanylyl cyclase beta 9.73 4.6.1.2
Nucleotide metabolism
33352 PF3D7_1203000
origin recognition complex subunit 1 9.47
DNA metabolism
33284 PF3D7_0306400 FAD-dependent glycerol-3-phosphate dehydrogenase, putative 9.36 1.1.5.3
Carbohydrate metabolism
33300 PF3D7_0525500 WD repeat-containing protein, putative 8.87
Unknown function
33295 PF3D7_0502000 vacuolar protein sorting-associated protein 11, putative 8.35
Intracellular traffic
33397 PF3D7_1410900 ribosome maturation protein SBDS, putative 8.30 Translation
33336 PF3D7_1027300
peroxiredoxin merozoite capping protein 1 7.97 1.11.1.15
Redox metabolism
33394 PF3D7_1366500 nucleoside diphosphate kinase 7.77 2.7.4.6
Nucleotide metabolism
33350 PF3D7_1147700
ATP synthase subunit delta, mitochondrial, putative 7.73 3.6.3.14
Organellar functions
33373 PF3D7_1311400
AP-1 complex subunit mu-1 7.37
Intracellular traffic
33272 PF3D7_0109000
photosensitized INA-labeled protein PHIL1 7.02
Invasion and motility
33358 PF3D7_1224000 GTP cyclohydrolase I 6.96 3.5.4.16
Nucleotide metabolism
33332 PF3D7_1020400 rRNA(cytosine-c(5))-methyltransferase, putative 6.51 2.1.1.12
RNA metabolism
33327 PF3D7_1003800 U5 small nuclear ribonucleoprotein component, putative 6.40
RNA metabolism
33333 PF3D7_1020500 ribosomal silencing factor rsfs, putative 6.11
Translation
33405 PF3D7_1437200 ribonucleoside-diphosphate reductase large subunit, putative 5.75 1.17.4.1
Nucleotide metabolism
33401 PF3D7_1420400
glycine--tRNA ligase 5.40 6.1.1.14
Translation
33305 PF3D7_0702000 Plasmodium exported protein (hyp12), unknown function 5.32
Protein export
33375 PF3D7_1315900 exportin-T, putative 5.07
Transport
33291 PF3D7_0423100 AP-4 complex subunit sigma, putative 3.93
Intracellular traffic
33395 PF3D7_1401300
proline aminopeptidase -3.53 3.4.11.5
Amino acid metabolism
33288 PF3D7_0324700 erythrocyte membrane protein 1 (PfEMP1), exon 2, pseudogene -5.21 Protein export
33331 PF3D7_1017500
myosin essential light chain ELC -5.65
Invasion and motility
33411 PF3D7_1465800
dynein beta chain, putative -6.21
Invasion and motility
33385 PF3D7_1352100 ABC transporter B family member 6, putative, ABCB6 -7.37
Transport
33320 PF3D7_0913500 protease, putative -8.12
Post translational modification
33368 PF3D7_1303500 sodium/hydrogen exchanger, Na+, H+ antiporter NHE -8.17
Transport
33335 PF3D7_1022600 kelch protein K10 -8.87
Post translational modification
33329 PF3D7_1009000 diphthine methyl ester synthase, putative -8.94 2.1.1.314
Post translational modification
33410 PF3D7_1453400 gamma-tubulin complex component, putative -9.73
Invasion and motility
33330 PF3D7_1014400 MO15-related protein kinase -9.73 2.7.11.22
DNA metabolism
33399 PF3D7_1413800 diphthamide biosynthesis protein 1, putative -9.92 6.3.2.22
Post translational modification
33338 PF3D7_1030200 claudin-like apicomplexan microneme protein -10.04
Invasion and motility
33386 PF3D7_1352200 U3 small nucleolar RNA-associated protein 15, putative -10.19
RNA metabolism
33276 PF3D7_0201600
PHISTb domain-containing RESA-like protein 1 -10.36
Protein export
33322 PF3D7_0918900
gamma-glutamylcysteine synthetase -10.37 6.3.2.2
Redox metabolism
33389 PF3D7_1355300
histone-lysine N-methyltransferase, putative -10.44 2.1.1.43
Histone modifications
33314 PF3D7_0821100 protein kinase 1 -10.56 2.7.11.1
Post translational modification
33378 PF3D7_1330000 pith domain-containing protein, putative -10.91
Post translational modification
33297 PF3D7_0511300 MORN repeat protein, putative -10.93
Post translational modification
33408 PF3D7_1445100 histidine--tRNA ligase, putative -10.98 6.1.1.21
Translation
33356 PF3D7_1218600 arginine-tRNA ligase; arginyl-tRNA synthetase -11.61 6.1.1.19
Translation
33292 PF3D7_0423500
glideosome associated protein with multiple membrane spans 2 -11.72
Invasion and motility
33377 PF3D7_1325000 U6 snRNA-associated Sm-like protein LSm6, putative -11.95
RNA metabolism
33323 PF3D7_0926100 protein kinase, putative -12.90 2.7.11.1
Post translational modification
33346 PF3D7_1127000 protein phosphatase, putative -12.91 3.1.3.16
Post translational modification
33342 PF3D7_1104200 chromatin remodeling protein -13.18
Histone modifications
33362 PF3D7_1231600 pre-mRNA-splicing factor ATP-dependent RNA helicase PRP2, putative -13.23 3.6.4.13
RNA metabolism
33391 PF3D7_1357700 U3 small nucleolar RNA-associated protein 21, putative -13.63
RNA metabolism
33348 PF3D7_1138100 ubiquitin-related modifier 1, putative -14.31
Post translational modification
33319 PF3D7_0909300
apoptosis-related protein -14.46 Post translational modification
33313 PF3D7_0815600 eukaryotic translation initiation factor 3 subunit G, putative -14.53 Translation
33307 PF3D7_0712600 erythrocyte membrane protein 1, PfEMP1 -14.55
Protein export
33321 PF3D7_0914600 transcription elongation factor 1, putative -15.28
RNA metabolism
33383 PF3D7_1341900 V-type proton ATPase subunit D, putative -15.41 3.6.3.14
Transport
33367 PF3D7_1301900 Plasmodium exported protein, unknown function -15.45 Protein export
33345 PF3D7_1125800 kelch domain-containing protein, putative -15.90
Unknown function
33298 PF3D7_0523400 DnaJ protein, putative -15.93
Post translational modification
33409 PF3D7_1447300 mitochondrial ribosomal protein S14 precursor, putative -16.40
Organellar functions
33279 PF3D7_0208000 serine repeat antigen 1 -16.67 3.4.22.-
Post translational modification
33363 PF3D7_1237800
ubiquitin-like modifier HUB1, putative -16.72 Post translational modification
33360 PF3D7_1229800
myosin J -17.24
Invasion and motility
33317 PF3D7_0902500
serine/threonine protein kinase, FIKK family -17.29 2.7.11.1
Post translational modification
33393 PF3D7_1361400 actin-depolymerizing factor 2 -17.34
Invasion and motility
33354 PF3D7_1207100 pre-rRNA-processing protein esf1, putative -17.60
RNA metabolism
33369 PF3D7_1305400 AAR2 protein, putative -17.79
RNA metabolism
33390 PF3D7_1355700 NLI interacting factor-like phosphatase, putative -18.11 3.1.3.16
Post translational modification
33952 PF3D7_1353200
membrane associated histidine-rich protein 2 -18.45 Protein export
33277 PF3D7_0207000
merozoite surface protein 4 -18.56
Invasion and motility
33278 PF3D7_0207500
serine repeat antigen 6 -18.88 3.4.22.-
Invasion and motility
33326 PF3D7_0936800
Plasmodium exported protein (PHISTc), unknown function -19.34
Protein export
33318 PF3D7_0904700
bacterial histone-like protein -19.52
Histone modifications
33283 PF3D7_0301300
epoxide hydrolase 1 -19.73
Protein export
33315 PF3D7_0822300 small nuclear ribonucleoprotein G, putative -20.22
RNA metabolism
33388 PF3D7_1355200 RAP protein, putative -21.11
Unknown function
33347 PF3D7_1137100 ribosomal protein s9, mitochondrial, putative -21.15
Organellar functions
33275 PF3D7_0111500 UMP-CMP kinase, putative -21.52 2.7.4.14
Nucleotide metabolism
33294 PF3D7_0501700 anaphase-promoting complex subunit 3, putative -22.56 Chromosome structure
33349 PF3D7_1141600
dolichol-phosphate mannosyltransferase -22.61 2.4.1.83
Lipid metabolism
33281 PF3D7_0212600
secreted protein with altered thrombospondin repeat domain -22.92
Protein export
33365 PF3D7_1248000 tRNA-splicing endonuclease, putative -24.69 4.6.1.16
RNA metabolism
33381 PF3D7_1334600 MSP7-like protein -24.76
Invasion and motility
33282 PF3D7_0220800
cytoadherence linked asexual protein 2 -26.61
cytoad
33359 PF3D7_1227900 RNA pseudouridylate synthase, putative -27.71 4.2.1.70
RNA metabolism
33310 PF3D7_0720700 phosphoinositide-binding protein, putative -28.44
Lipid metabolism
33273 PF3D7_0109600 cold-shock protein, putative -29.73
Post translational modification
33290 PF3D7_0414900
armadillo-domain containing rhoptry protein -30.80
Invasion and motility
33316 PF3D7_0902200
serine/threonine protein kinase, FIKK family -30.92 2.7.11.1
Post translational modification
33293 PF3D7_0424300 erythrocyte binding antigen-165, pseudogene -33.55
Invasion and motility
33341 PF3D7_1036000
merozoite surface protein 11 -35.16
Invasion and motility
33412 PF3D7_1475000 mediator of RNA polymerase ii transcription subunit 31, putative -39.54
RNA metabolism
33370 PF3D7_1306800 RED-like protein, putative -39.73 Unknown function
33382 PF3D7_1335100
merozoite surface protein 7 -44.15
Invasion and motility
+72  conserved Plasmodium protein, unknown function
Online articles related to Effect of hyperoxia on gene expression retrieved from PubMed