Differentially expressed genes in 3D7 strain treated for 5h with melatonin
Lima WR, Tessarin-Almeida G, Rozanski A, Parreira KS, Moraes MS, Martins DC, Hashimoto RF, Galante PA, Garcia CR. Signaling transcript profile of the asexual intraerythrocytic development cycle of Plasmodium falciparum induced by melatonin and cAMP. Genes Cancer. 2016 7(9-10):323-339. PMID: 28050233
New PfID Old PfID Annotation Fold change EC# Transcript
PF3D7_1116600 PF11_0173 oligosaccharyl transferase STT3 subunit, putative 7 2.4.99.18
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PF3D7_0317300 PFC0760c conserved Plasmodium protein, unknown function 6.2
PF3D7_1024800 PF10_0242
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conserved Plasmodium protein, unknown function 6.2
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PF3D7_0722400 MAL7P1.122 GTP-binding protein, putative 6.1
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PF3D7_1108500 PF11_0097 succinyl-CoA synthetase alpha subunit, putative 5.8 6.2.1.4
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PF3D7_1237600 PFL1820w rRNA processing WD-repeat protein, putative 5.8
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PF3D7_0707800 MAL7P1.23 RAP protein, putative 5.3
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PF3D7_1238800 PFL1880w acyl-CoA synthetase (ACS11) 5.3 6.2.1.3
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PF3D7_1239000 PFL1890c HD superfamily phosphohydrolase protein 5.3 3.1.4.17
PF3D7_1209300 PFL0465c
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telomere repeat-binding zinc finger protein, putative 5.3
PF3D7_1328900 PF13_0151 pub domain-containing protein, putative 5.3 3.5.1.52
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PF3D7_0708500 PF07_0030 heat shock protein 86 family protein 4.9
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PF3D7_0913500 PFI0660c protease, putative 4.9
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PF3D7_1118800 PF11_0195 conserved Plasmodium protein, unknown function 4.5
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PF3D7_0518500 PFE0925c
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ATP-dependent RNA helicase DDX23, putative (DDX23) 4.4 3.6.4.13
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PF3D7_0501700 PFE0085c anaphase-promoting complex subunit 3, putative 4.4
PF3D7_1406400 PF14_0061 PPR repeat protein (PPR) 4.4
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PF3D7_1440100 PF14_0380 conserved Plasmodium protein, unknown function 4.4
PF3D7_1323900 PF13_0136 conserved Plasmodium protein, unknown function 4.4
PF3D7_1342600 PF13_0233
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myosin A (MyoA) 3.9
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PF3D7_0305400 PFC0241w conserved Plasmodium protein, unknown function 3.8
PF3D7_0724300 MAL7P1.130 3-demethylubiquinone-9 3-methyltransferase, putative 3.4 2.1.1.64
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PF3D7_1428900 PF14_0268 conserved Plasmodium protein, unknown function 3.4
PF3D7_0206500 PFB0285c conserved Plasmodium protein, unknown function 3.3
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PF3D7_1338100 MAL13P1.190 26S proteasome regulatory subunit RPN3, putative (RPN3) 3.3
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PF3D7_0103800 PFA0190c actin-related protein (ARP1) 3.1
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PF3D7_0627800 PFF1350c acetyl-CoA synthetase, putative (ACS) 2.9 6.2.1.1
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PF3D7_0404700 PFD0230c
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dipeptidyl aminopeptidase 3 (DPAP3) 2.7 3.4.14.4
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PF3D7_1368200 MAL13P1.344
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RNAse L inhibitor protein, putative 2.7
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PF3D7_0810500 MAL8P1.108 protein phosphatase, putative 2.6 3.1.3.16
PF3D7_1428200 PF14_0260 major facilitator superfamily domain-containing protein, putative 2.6
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PF3D7_1410500 PF14_0103 conserved Plasmodium protein, unknown function 2.5
PF3D7_0703500 MAL7P1.12
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erythrocyte membrane-associated antigen 2.5
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PF3D7_0724700 MAL7P1.134 conserved Plasmodium protein, unknown function 2.5
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PF3D7_1211900 PFL0590c
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non-SERCA-type Ca2+ -transporting P-ATPase (ATP4) 2.5 3.6.3.8
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PF3D7_1411900 PF14_0117 p1/s1 nuclease, putative 2.4 3.1.30.1
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PF3D7_1029600 PF10_0289
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adenosine deaminase (ADA) 2.4 3.5.4.4
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PF3D7_1200200 PFL0010c rifin,PIR protein (RIF) 2.3
PF3D7_0316600 PFC0725c
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formate-nitrite transporter, putative 2.3
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PF3D7_0817600 PF08_0058
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conserved Plasmodium protein, unknown function 2.2
PF3D7_0404000 PFD0195c conserved Plasmodium protein, unknown function 2.2
PF3D7_1238900 PFL1885c
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protein kinase 2 (PK2) 2.2 2.7.11.1
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PF3D7_1430100 PF14_0280
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serine/threonine protein phosphatase 2A activator (PTPA) 2.2
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PF3D7_1011500 PF10_0112 conserved Plasmodium membrane protein, unknown function 2.1
PF3D7_1216200 PFL0780w glycerol-3-phosphate dehydrogenase [NAD+], putative 2.1 1.1.1.8
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PF3D7_0917900 PFI0875w
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heat shock protein 70 (HSP70-2) 2.1
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PF3D7_1217000 PFL0820c conserved Plasmodium protein, unknown function 2
PF3D7_0406500 PFD0320c conserved Plasmodium protein, unknown function 2
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PF3D7_0207700 PFB0345c
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serine repeat antigen 4 (SERA4) 2 3.4.22.-
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PF3D7_1334700 PF13_0194
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MSP7-like protein (MSRP7) 0.5
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PF3D7_1335600 MAL13P1.178 conserved Plasmodium protein, unknown function 0.5
PF3D7_1249400 PFL2370c conserved Plasmodium protein, unknown function 0.5
PF3D7_0905400 PFI0265c
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high molecular weight rhoptry protein 3 (RhopH3) 0.5
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PF3D7_0929400 PFI1445w
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high molecular weight rhoptry protein 2 (RhopH2) 0.5
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PF3D7_1303500 PF13_0019
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sodium/hydrogen exchanger, Na+, H+ antiporter (NHE) 0.4
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PF3D7_0204900 PFB0220w 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial, putative 0.4 2.1.1.201
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PF3D7_1362400 MAL13P1.310
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calpain (Pcalp) 0.4 3.4.22.-
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PF3D7_0313100 PFC0550w ubiquitin-protein ligase, putative (HRD3) 0.4 6.3.2.19
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PF3D7_1019600 PF10_0189 conserved Plasmodium protein, unknown function 0.4
PF3D7_1413600 PF14_0134 conserved Plasmodium protein, unknown function 0.4
PF3D7_1343600 MAL13P1.218 UDP-N-acetylglucosamine pyrophosphorylase, putative 0.4 2.7.7.23
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PF3D7_1452800 PF14_0503 conserved Plasmodium protein, unknown function 0.4
PF3D7_0717700 PF07_0073
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serine--tRNA ligase, putative 0.3 6.1.1.11
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PF3D7_0411900 PFD0590c DNA polymerase alpha 0.3 2.7.7.7
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PF3D7_1466400 PF14_0633 AP2 domain transcription factor AP2-EXP 0.3
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PF3D7_1339900 PF13_0218
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ABC transporter (MDR family), putative (MDR5) 0.3 3.6.3.44
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PF3D7_0303900 PFC0176c phosphatidylethanolamine-binding protein, putative 0.3
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PF3D7_0506900 PFE0340c
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rhomboid protease ROM4 (ROM4) 0.3 3.4.21.105
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PF3D7_0505300 PFE0260w UDP-n-acetylglucosamine transporter, putative 0.3
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PF3D7_1411700 PF14_0115 conserved protein, unknown function 0.3
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PF3D7_0931700 PFI1540w conserved Plasmodium protein, unknown function 0.3
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PF3D7_1447000 PF14_0448 40S ribosomal protein S5 0.3
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PF3D7_0509000 PFE0445c conserved Plasmodium protein, unknown function 0.3
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PF3D7_1363100 PF13_0333 conserved Plasmodium protein, unknown function 0.3
PF3D7_0809500 MAL8P1.114 histone acetyltransferase subunit NuA4, putative 0.2
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PF3D7_1249900 PFL2395c ribosomal RNA small subunit methyltransferase a2, putative 0.2
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PF3D7_0400200 PFD0010w erythrocyte membrane protein 1 (PfEMP1), exon 2, pseudogene 0.2
PF3D7_0423600 PFD1115c conserved Plasmodium protein, unknown function 0.2
PF3D7_0402400 PFD0115c
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Plasmodium exported protein, unknown function (GEXP18) 0.2
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PF3D7_0509000 PFE0445c conserved Plasmodium protein, unknown function 0.2
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PF3D7_0217800 PFB0830w 40S ribosomal protein S26 (RPS26) 0.2
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PF3D7_1017200 PF10_0167
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enoyl-CoA hydratase-related protein, putative 0.2 4.2.1.17
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PF3D7_0310700 PFC0445w trafficking protein particle complex subunit 4, putative 0.2
PF3D7_0216000 PFB0730w DEAD/DEAH box helicase, putative 0.2 3.6.4.13
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PF3D7_1251600 PFL2480w conserved Plasmodium protein, unknown function 0.1
PF3D7_1205800 PFL0290w high mobility group protein B3, putative (HMGB3) 0.1
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PF3D7_1334800 MAL13P1.174
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MSP7-like protein (MSRP2) 0.1
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PF3D7_1229300 PFL1415w conserved Plasmodium protein, unknown function 0.1
PF3D7_1116000 PF11_0168
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rhoptry neck protein 4 (RON4) 0.1
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PF3D7_1011000 PF10_0107 inner membrane complex sub-compartment protein 1, putative (ISP1) 0.1
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Online articles related to Differentially expressed genes in 3D7 strain treated for 5h with melatonin retrieved from PubMed