Malaria Parasite Metabolic Pathways
Drugs affecting pathway with unknown specific target
| Drug Name | PubMed Articles (year of publication) |
|---|---|
| Suggested target |
Selenocysteine biosynthesis map details
| PFID | PFID Old | Annotation | Formal Annotation | EC | Transcript |
|---|---|---|---|---|---|
| PF3D7_1205100 | PFL0255c | O-phosphoseryl-tRNA:selenocysteinyl-tRNA synthase SLA/LP | O-phosphoseryl-tRNA(Sec) selenium transferase, putative | 2.9.1.2 |
|
| PF3D7_0103700 | PFA0185w | PSTK | L-seryl-tRNA(Sec) kinase, putative | 2.7.1.164 | |
| PF3D7_0309700 | PFC0405c | SECIS Binding Protein | SECIS-binding protein 2, putative |
|
|
| PF3D7_0629400 | PFF1425w | SECp43 | polyadenylate-binding protein 3, putative |
|
|
PF3D7_1403600
|
PF14_0033 | Sel1 gene, selenoprotein | selenoprotein |
|
|
|
PF3D7_0931200
|
PFI1515w | Sel2 gene, selenoprotein | selenoprotein | ||
|
PF3D7_0815000
|
MAL8P1.86 | Sel3 gene, selenoprotein | selenoprotein |
|
|
|
PF3D7_1427200
|
PF14_0251 | Sel4 gene, selenoprotein | selenoprotein |
|
|
| PF3D7_0910400 | PFI0505c | Selenide, water dikinase | selenide water dikinase, putative | 2.7.9.3 |
|
| PF3D7_1438200 | MAL14_tRNA.SelCys1 | Selenocysteine tRNA (tRNASec) | tRNA Selenocysteine | ||
| PF3D7_0110100 | PFA0495c | selenocysteine-specific elongation factor, putative | selenocysteine-specific elongation factor, putative |
|
|
|
PF3D7_0717700
|
PF07_0073 | Ser-tRNA ligase | serine--tRNA ligase, putative | 6.1.1.11 |
|
| PF3D7_1216000 | PFL0770w | Ser-tRNA ligase | serine--tRNA ligase, putative | 6.1.1.11 |
|
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 | PFA0185w | L-seryl-tRNA(Sec) kinase, putative |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 | PFA0495c | selenocysteine-specific elongation factor, putative |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 | PFC0405c | SECIS-binding protein 2, putative |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 | PFF1425w | polyadenylate-binding protein 3, putative |
Total number of related proteins: 2
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PF07_0073
|
serine--tRNA ligase, putative |
| 2 | PFL0770w | serine--tRNA ligase, putative |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
MAL8P1.86
|
selenoprotein |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 | PFI0505c | selenide water dikinase, putative |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PFI1515w
|
selenoprotein |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 | PFL0255c | O-phosphoseryl-tRNA(Sec) selenium transferase, putative |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PF14_0033
|
selenoprotein |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PF14_0251
|
selenoprotein |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 | MAL14_tRNA.SelCys1 | tRNA Selenocysteine |