Genes coding for transport proteins
Source: Martin RE, Henry RI, Abbey JL, Clements JD, Kirk K. The 'permeome' of the malaria parasite: an overview of the membrane transport proteins of Plasmodium falciparum. Genome Biology 2005, 6:R26. added putative function
Transport families are assigned according to Transport Classification Database http://www.tcdb.org/tcdb/. Click on TC number to get into the DB.
TC/PfID Putative function Transcript EC
TC 1.A alpha-Type channels
TC 1.A.1 VOLTAGE-GATED ION CHANNEL SUPERFAMILY
PFL1315w
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potassium channel K1
PF14_0342 Ion channel, putative
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PF14_0622
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potassium channel K2
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TC 1.A.8.2.2 MIXED FUNCTION GLYCEROL FACILITATOR/AQUAPORIN, GlpF
PF11_0338
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Aquaglyceroporin
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TC 1.A.23 SMALL CONDUCTANCE MECHANOSENITIVE ION CHANNEL (MSCS) FAMILY
PF11_0092
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Mechanosensitive ion channel
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TC 1.A.35 CorA METAL ION TRANSPORTER FAMILY
PF14_0255 CorA-like Mg2+ transporter protein, putative
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PF11_0210 Metal ion channel - Mg2+, Co2+ and Ni2+
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MAL13P1.23 CorA-like Mg2+ transporter protein, putative
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TC 1.A.56 COPPER TRANSPORTER (Ctr) FAMILY
PF14_0211
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Copper channel
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PF14_0369
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Copper transporter putative
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TC 1.A.67
PFC0282w ER membrane protein complex subunit 5, putative
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ION CHANNEL-ADENYLATE CYCLASE FAMILY activity of ion channel domain not confirmed; family yet to be included in the TC system
PF14_0788
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Protein with ion channel and adenylate cyclase domains
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4.6.1.1
TC 1.B
TC 1.B.8.1.1 VOLTAGE-DEPENDENT ANION CHANNEL (VDAC) PORIN
PF14_0301 Voltage-dependent anion-selective channel protein, putative
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TC 2.A Electrochemical Potential-driven Transporters
TC 2.A.1 MAJOR FACILITATOR SUPERFAMILY
PFL0170w Transporter
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TC 2.A.1.1 SUGAR PORTER FAMILY
PFB0210c
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Hexose transporter 1 (PfHT1)
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PFI0955w Sugar transporter, putative
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PFI0785c
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major facilitator superfamily domain-containing protein
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TC 2.A.1.2
PFB0275w
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Pantothenate transporter
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PF11_0059 Metabolite/drug transporter
PF14_0260 major facilitator superfamily domain-containing protein, putative
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PF14_0387 major facilitator superfamily domain-containing protein
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PFE0825w
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major facilitator superfamily domain-containing protein, putative
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TC 2.A.1.13 MONOCARBOXYLATE PORTER FAMILY/ OXALATE:FORMATE ANTIPORTER FAMILY
TC 2.A.1.11 MONOCARBOXYLATE PORTER FAMILY/ OXALATE:FORMATE ANTIPORTER FAMILY
PFB0465c
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Monocarboxylate transporter
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PFI1295c
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Monocarboxylate transporter
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TC 2.A.1.25 PEPTIDE-ACETYL COENZYME A TRANSPORTER FAMILY
PF10_0360 Acetyl-CoA transporter
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TC 2.A.2 GLYCOSIDE-PENTOSIDE-HEXURONIDE:CATION SYMPORTER FAMILY
PFE1455w Sugar transporter, putative; Sugar:cation symporter
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TC 2.A.60 ORGANO ANION TRANSPORTER FAMILY
PFF0690c major facilitator superfamily-related transporter
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TC 2.A.71 FOLATE-BIOPTERIN TRANSPORTER FAMILY
MAL8P1.13
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folate/biopterin transporter, putative
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PF11_0172
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Folate/biopterin transporter
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PF10_0215 Conserved Plasmodium membrane protein, unknown function ; Metabolite/vitamin transporter
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NOVEL PUTATIVE TRANSPORTER FAMILY
PFA0240w Transporter, putative
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PFA0245w Transporter, putative
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PFC0530w major facilitator superfamily-related transporter, putative
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PFI0720w
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Transporter, putative
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PF11_0310 Transporter, putative
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TC 2.A.4 CATION DIFFUSION FACILITATOR (CDF) FAMILY
PF07_0065 Zinc transporter, putative
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TC 2.A.5
PFF0450c Zn2+ or Fe2+ permease
PF10_0216 Zinc transporter, putative
TC 2.A.6 Resistance-Nodulation-Cell Division Superfamily
TC 2.A.6.6 EUKARYOTIC (PUTATIVE) STEROL TRRANSPORTER FAMILY
PFA0375c npc1-related protein, putative
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TC 2.A.7 DRUG/METABOLIET TRANSPORTER SUPERFAMILY
PF07_0070
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drug/metabolite transporter dmt2 3.6.3.44
PFE0785c
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Drug/metabolite transporter; GDP-fucose transporter ?
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PF08_0013 magnesium transporter, putative
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TC 2.A.7.3 10 TMS DRUG/METABOLITE EXPORTER FAMILY
PF07_0064 drug/metabolite transporter dmt1, putative
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3.6.3.44
MAL7P1.27
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Chloroquine resistance transporter, PfCRT
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TC 2.A.7.9 TRIOSE-PHOSPHATE TRANSPORTER FAMILY
PFE0410w
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Triose- or hexose-Pi: Pi antiporter
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PFE1510c
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Phosphoenolpyruvate: Pi antiporter
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PFL0890c Triose- or hexose-Pi:Pi antiporter
TC 2.A.7.13 GDP-MANNOSE: GMP ANTIPORTER FAMILY
PFB0535w GDP-fucose:GMP antiporter, putative
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TC2.A.7.10 UDP-N-ACETYL GLUCOSAMINE: UMP ANTIPORTER FAMILY (TC 2.A.7.10)
PFE0260w UDP-N-acetyl glucosamine:UMP antiporter
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TC 2.A.7.11 UDP-GALACTOSE: UMP ANTIPORTER FAMILY
PF11_0141 UDP-galactose transporter, putative; UDP-galactose:UMP antiporter
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TC 2.A.18 AMINO ACID/AUXIN PERMEASE FAMILY
PFF1430c
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amino acid transporter aat1
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PFL0420w Amino acid transporter
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PFL1515c Amino acid transporter
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TC 2.A.19
PFF0170w
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Ca2+:H+ antiporter
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TC 2.A.20 INORGANIC PHOSPHATE TRANSPORTER FAMILY
MAL13P1.206
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Na+ -dependent Pi transporter, sodium-dependent phosphate transporter
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TC 2.A.22 NEUROTRANSMITTER:Na+ SYMPORTER FAMILY
PFB0435c Amino acid transporter, putative
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PFE0775c Amino acid transporter
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PF11_0334 Amino acid transporter, putative
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PF07_0055 H+:amino acid symporter
TC 2.A.29 MITOCHONDRIAL CARRIER (MC) FAMILY
PF10_0051 ADP/ATP antiporter
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PF10_0366
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ADP/ATP antiporter
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PFI0425w mitochondrial carrier protein, putative
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PFL2000w Transporter
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PF13_0359 Transporter
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PFI0255c Mitochondrial carrier protein, putative
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PFD0367w Mitochondrial carrier protein, putative
PF08_0031
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Dicarboxylate/tricarboxylate antiporter
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PFL0110c Pi : H+ symporter
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PF08_0093 Mitochondrial carrier protein, putative
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PFA0435w Hypothetical protein; mitochondrial carrier family
PFL1145w citrate/oxoglutarate carrier protein, putative
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PFA0415c Mitochondrial carrier protein, putative
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TC 2.A.36
PF13_0019
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Na+:H+ exchanger
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TC 2.A.44 FORMATE-NITRITE TRANSPORTER FAMILY
PFC0725c
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Formate-nitrite transporter
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TC 2.A.53 SULPHATE PERMEASE FAMILY
PF14_0679
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Inorganic anion exchanger, inorganic anion antiporter
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TC 2.A.55 METAL ION (Mn2+-IRON) TRANSPORTER FAMILY
PFE1185w Divalent cation (metal) :H+ symporter
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TC 2.A.57 EQUILIBRATIVE NUCLEOSIDE TRANSPORTER FAMILY
PFA0160c
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Nucleoside transporter
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MAL8P1.32
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Nucleoside transporter PfNT2
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PF13_0252
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Nucleoside transporter PfNT1
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PF14_0662 Nucleoside transporter
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TC 2.A.66.1 MULTI ANTIMICROBIAL EXTRUSION (MATE) FAMILY
Organic solutes/Na+ or H+ antiporter
TC 2.A.89 THE VACUOLAR IRON TRANSPORTER (VIT) FAMILY
PFL1140w Fe2+ transporter
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2.A.105 THE MITOHONDRIAL PYRUVATE CARRIER(MPC) FAMILY
PF13_0223 Mitochondrial pyruvate carrier protein 1
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PF14_0671 Mitochondrial pyruvate carrier protein 2, putative
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TC 3.A Primary Active P-P-bond-hydrolysis-driven Transporters
TC 3.A.1 ATP-BINDING CASSETTE (ABC) SUPERFAMILY
PFC0875w ABC transporter
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PF08_0098 ABC1 family, putative
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PF08_0078 ABC transporter, putative
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TC 3.A.1.209 MHC PEPTIDE TRANSPORTER (TAP) FAMILY
PFC0125w
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ABC transporter (TAP family)
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PF11_0466 ABC transporter (TAP family)
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PFL0495c
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ABC transporter (TAP family)
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TC 3.A.1.201 MULTIDRUG RESISTANCE EXPORTER (MDR) FAMILY
PFE1150w
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Multidrug resistance protein (MDR family) PfMDR1
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3.6.3.44
PF13_0218
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ABC transporter (MDR family)
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3.6.3.44
TC 3.A.1.210 DPL HEAVY METAL TRANSPORTER (HMT) FAMILY
PF13_0271
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ABC transporter (HMT family)
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PF14_0455
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Multidrug resistance protein 2 (HMT family) PfMDR2
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3.6.3.44
TC 3.A.1.208 CONJUGATE TRANSPORTER (CT) FAMILY
PFA0590w
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ABC transporter (CT family) PfMRP
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3.6.3.44
PFL1410c
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ABC transporter (CT family)
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3.6.3.44
TC 3.A.1.204 EPD EYE PIGMENT PRECURSOR TRANSPORTER (EPP) FAMILY
PF14_0244
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ABC transporter; EPP family
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TC 3.A.2
PF13_0065
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V-type proton ATPase catalytic subunit A
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3.6.3.14
PF08_0113
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v-type proton atpase subunit a, putative
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3.6.3.14
PFD0305c
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Vacuolar ATP synthase subunit B
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3.6.3.14
PFA0300c V-type ATPase, subunit C, putative
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3.6.3.14
PF13_0227
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Vacuolar ATP synthase subunit D, putative
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3.6.3.14
PFI1670c Vacuolar ATP synthase subunit E, putative
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3.6.3.14
PF11_0412 Vacuolar ATP synthase subunit F, putative
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3.6.3.14
PF13_0130 Vacuolar ATP synthase subunit G, putative
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3.6.3.14
PF14_0615 ATP synthase (C/AC39 or D) subunit, putative
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3.6.3.14
PF13_0034 Vacuolar ATP synthase subunit H, putative
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3.6.3.14
PFE0965c
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Vacuolar ATP synthetase, putative; 16 kDa proteolipid subunit
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3.6.3.14
MAL13P1.271 V-type ATPase, putative
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3.6.3.14
PFB0795w
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ATP synthase subunit alpha, mitochondrial
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3.6.3.14
PFL1725w
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ATP synthase subunit beta, mitochondrial
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3.6.3.14
PF11_0485
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ATP synthase subunit delta, mitochondrial, putative
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3.6.3.14
MAL13P1.47
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ATP synthase subunit o, mitochondrial, putative
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3.6.3.14
PF13_0061
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ATP synthase subunit gamma, mitochondrial
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3.6.3.14
MAL7P1.75
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ATP synthase subunit epsilon, mitochondrial, putative 3.6.3.14
MAL7P1.340
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ATP synthase subunit C, putative
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3.6.3.14
TC 3.A.3 P-TYPE ATPase (P-ATPase) SUPERFAMILY
PFA0310c
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SERCA-type Ca2+-transporting P-ATPase (PfATPase6)
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3.6.3.8
PFL0590c
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Non-SERCA-type Ca2+-transporting PATPase; PfATPase4
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3.6.3.8
MAL13P1.246 E1-E2 ATPase, putative
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PFI0240c
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Cu2+-transporting P-ATPase; PfCuP-ATPase
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3.6.3.4
PFE0195w Cation-transporting P-ATPase; PfATPase3
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3.6.3.12
PFE0805w
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Cation-transporting P-ATPase; PfATPase1
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3.6.3.12
PF07_0115
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Cation transporting ATPase, cation transporter
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3.6.3.12
PFC0840w Aminophospholipid-transporting P-ATPase, PfATPase7
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3.6.3.1
PFL0950c
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Aminophospholipid-transporting P-ATPase; PfATPase2
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3.6.3.1
PFL1125w Aminophospholipid-transporting P-ATPase
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3.6.3.1
PF14_0654 Aminophospholipid transporting P-ATPase, putative
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3.6.3.1
TC 3.A.10
PFL1700c
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V-type K+-independent H+-translocating inorganic pyrophosphatase; PfVP2
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3.6.1.1
PF14_0541
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V-type H+-translocating pyrophosphatase, putative
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3.6.1.1
TC 3.A.19 THE TMS RECOGNITION/INSERTION COMPLEX (TRC) FAMILY
PFD0725c
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Arsenical pump-driving ATPase, putative
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Proteins that have the predicted structural characteristics of a transporter, but which do not share sequence similarities with known or putative transport proteins and/or conserved domains of transport protein families.
PFB0770c tmem121 domain-containing protein, putative
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PFI1205c Conserved Plasmodium membrane protein, unknown function
MAL8P1.30 Conserved Plasmodium membrane protein, unknown function
MAL8P1.135 dpy-19-like c-mannosyltransferase
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2.4.1.-
PFL2410w csc1-like protein, putative, phosphate transporter
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PF13_0172 Conserved Plasmodium membrane protein, unknown function
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PFC0240c Conserved Plasmodium membrane protein, unknown function
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PFC0685w Conserved Plasmodium membrane protein, unknown function
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PFE1525w Conserved Plasmodium membrane protein, unknown function
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PF11_0363 Conserved Plasmodium membrane protein, unknown function
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Online articles related to Genes coding for transport proteins retrieved from PubMed

RX Drugs affecting pathway with unknown specific target