Immunofluorescence staining of mature schizonts of P. falciparum K1 by anti-35.1 MAb SP8.18 (A) and anti-rRAP-123–711 MAb RAP1-14 (C). Both MAbs exhibited a double-dot staining pattern characteristic for rhoptry-associated proteins. Parasite DNA was stained using Hoechst 33258 dye (B and D).

Moreno R, Pöltl-Frank F, Stüber D, Matile H, Mutz M, Weiss NA, Pluschke G. Rhoptry-associated protein 1-binding monoclonal antibody raised against a heterologous peptide sequence inhibits Plasmodium falciparum growth in vitro. Infect Immun. 2001 69:2558-68.