Localisation of SBP-1 in normal and protein 4.1R-deficient red blood cells. Representative confocal immunofluorescence images of normal (A) and 4.1R-deficient (C) RBCs immunolabelled for Maurer's clefts (SBP1; green) and the RBCmembrane skeleton (Glycophorin A, GpA; red). This data strongly supports that the interaction between SBP1-C and protein 4.1R plays a significant role in localising Maurer's clefts to their final destination in the PRBC, tethered to the RBC membrane skeleton.

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