You can find more information about 1-deoxy-D-xylulose-5-phosphate synthase using the following links:

Affecting Drugs
Drug Name	PubMed Articles (year of publication)
Biochemical analyses, suggested target	Mechanistic binding insights for 1-deoxy-D-Xylulose-5-Phosphate synthase, the enzyme catalyzing the first reaction of isoprenoid biosynthesis in the malaria-causing protists, Plasmodium falciparum and Plasmodium vivax(2016)
Ketoclomazone	Methylerythritol phosphate pathway to isoprenoids: kinetic modeling and in silico enzyme inhibitions in Plasmodium falciparum(2013)
structural analysis, suggested target	Computational analysis, structural modeling and ligand binding site prediction of Plasmodium falciparum 1-deoxy-d-xylulose-5-phosphate synthase(2017)