You can find more information about
peptidyl-prolyl cis-trans isomerase
using the following links:
PlasmoDB - the Plasmodium genome resource
The TDR Targets Database
PDB protein strucure
1QNH
1QNG
2FU0
Affecting Drugs
Drug Name
PubMed Articles (year of publication)
[3’-keto-MeBmt] cyclosporin D
Cyclosporin-binding proteins of Plasmodium falciparum(2003)
Cyclosporin a
Plasmodium falciparum calcineurin and its association with heat shock protein 90: mechanisms for the antimalarial activity of cyclosporin A and synergism with geldanamycin(2005)
Overexpression, purification and assessment of cyclosporin binding of a family of cyclophilins and cyclophilin-like proteins of the human malarial parasite Plasmodium falciparum(2011)
Immunophilin-protein interactions in Plasmodium falciparum(2015)
cyclosporin A
New leads for drug repurposing against malaria(2019)
Structural insights into Plasmodium PPIases(2022)
Fk506
Immunophilin-protein interactions in Plasmodium falciparum(2015)
Geldanamycin
Plasmodium falciparum calcineurin and its association with heat shock protein 90: mechanisms for the antimalarial activity of cyclosporin A and synergism with geldanamycin(2005)