You can find more information about pyruvate kinase using the following links:

PDB protein strucure

• 6KSH
• 3KHD

Affecting Drugs
Drug Name	PubMed Articles (year of publication)
Artemisinin	Haem-activated promiscuous targeting of artemisinin in Plasmodium falciparum(2015)
Difference from host enzyme, suggested target	Plasmodium falciparum pyruvate kinase as a novel target for antimalarial drug-screening(2007)
mutation	Prominent role of cysteine residues C49 and C343 in regulating Plasmodiumfalciparum pyruvate kinase activity(2022)
Suramin	Pyruvate kinase from Plasmodium falciparum: Structural and kinetic insights into the allosteric mechanism(2020)
VKRWKKWWRKWKKWV-NH2	In Vitro and In Vivo Antimalarial Activity of LZ1, a Peptide Derived from Snake Cathelicidin(2019)