You can find more information about topoisomerase I using the following links:

Affecting Drugs
Drug Name	PubMed Articles (year of publication)
Camptothecin	Effects of camptothecin, a topoisomerase I inhibitor, on Plasmodium falciparum(1998) Antimalarial drug targets in Plasmodium falciparum predicted by stage-specific metabolic network analysis(2010) Replacement of the human topoisomerase linker domain with the plasmodial counterpart renders the enzyme camptothecin resistant(2013) Theoretical and experimental studies of new modified isoflavonoids as potential inhibitors of topoisomerase I from Plasmodium falciparum(2014)
Peptide wrwycrck	Peptide Inhibition of Topoisomerase IB from Plasmodium falciparum(2011)
Topotecan	Theoretical and experimental studies of new modified isoflavonoids as potential inhibitors of topoisomerase I from Plasmodium falciparum(2014)