You can find more information about Topoisomerase I using the following links:

PFID

PFID Old

Formal Annotation

PlasmoDB

TDR Targets

Subcellular Localization

Affecting Drugs

Drug Name

PubMed Articles (year of publication)

PF3D7_0510500

PFE0520c

topoisomerase I

Camptothecin	Effects of camptothecin, a topoisomerase I inhibitor, on Plasmodium falciparum Antimalarial drug targets in Plasmodium falciparum predicted by stage-specific metabolic network analysis Replacement of the human topoisomerase linker domain with the plasmodial counterpart renders the enzyme camptothecin resistant Theoretical and experimental studies of new modified isoflavonoids as potential inhibitors of topoisomerase I from Plasmodium falciparum
Peptide wrwycrck	Peptide Inhibition of Topoisomerase IB from Plasmodium falciparum
Topotecan	Theoretical and experimental studies of new modified isoflavonoids as potential inhibitors of topoisomerase I from Plasmodium falciparum

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Brenda - The Comprehensive Enzyme Information System