You can find more information about Protein kinase using the following links:

Imatinib mesylate	Tyrosine kinase inhibitors: New class of antimalarials on the horizon?
Sorafenib Tosylate	Tyrosine kinase inhibitors: New class of antimalarials on the horizon?

PF3D7_0213400

PFB0605w

protein kinase 7

PlasmoDB

TDR

Picture 1

1nm-pp1	Structures of P. falciparum protein kinase 7 identify an activation motif and leads for inhibitor design
3-(1,2,3-triazol-4-yl)pyrazolo[3,4-d]pyrimidin	Synthesis of 3-(1,2,3-triazol-1-yl)- and 3-(1,2,3-triazol-4-yl)-substituted pyrazolo[3,4-d]pyrimidin-4-amines via click chemistry: potential inhibitors of the Plasmodium falciparum PfPK7 protein kinase
Hymenialdisine	PfPK7, an atypical MEK-related protein kinase, reflects the absence of classical three-component MAPK pathways in the human malaria parasite Plasmodium falciparum
Hymenialdisine 01	PfPK7, an atypical MEK-related protein kinase, reflects the absence of classical three-component MAPK pathways in the human malaria parasite Plasmodium falciparum
Imidazopyridazine	Synthesis and in vitro evaluation of imidazopyridazines as novel inhibitors of the malarial kinase PfPK7 Structural insight for imidazopyridazines as malarial kinase PfPK7 inhibitors using QSAR techniques
Luzindole	Ubiquitin proteasome system and the atypical kinase PfPK7 are involved in melatonin signaling in Plasmodium falciparum
Melatonin	Ubiquitin proteasome system and the atypical kinase PfPK7 are involved in melatonin signaling in Plasmodium falciparum
Pp2	Structures of P. falciparum protein kinase 7 identify an activation motif and leads for inhibitor design
pyrazolo[3,4-d]pyrimidin-4-amine	Synthesis of 3-(1,2,3-triazol-1-yl)- and 3-(1,2,3-triazol-4-yl)-substituted pyrazolo[3,4-d]pyrimidin-4-amines via click chemistry: potential inhibitors of the Plasmodium falciparum PfPK7 protein kinase
Staurosporine	PfPK7, an atypical MEK-related protein kinase, reflects the absence of classical three-component MAPK pathways in the human malaria parasite Plasmodium falciparum
TCMDC-136692	Biochemical Screening of Five Protein Kinases from Plasmodium falciparum against 14,000 Cell-Active Compounds
TCMDC-136693	Biochemical Screening of Five Protein Kinases from Plasmodium falciparum against 14,000 Cell-Active Compounds

PF3D7_0214600

PFB0665w

serine/threonine protein kinase stk2, putative

PlasmoDB

TDR

PF3D7_0301200

PFC0060c

serine/threonine protein kinase, FIKK family

PlasmoDB

TDR

PF3D7_0302100

PFC0105w

serine/threonine protein kinase

PlasmoDB

TDR

4-(1h)-quinolone	Inhibition of the SR protein-phosphorylating CLK kinases of Plasmodium falciparum impairs blood stage replication and malaria transmission
Aminopyrimidines	Inhibition of the SR protein-phosphorylating CLK kinases of Plasmodium falciparum impairs blood stage replication and malaria transmission
Annomontin	Synthesis of desaza analogues of annomontine and canthin-4-one alkaloids
In silico prediction of protein targets of antimalarial compounds, suggested target	Prediction of the P. falciparum target space relevant to malaria drug discovery

PF3D7_0309200

PFC0385c

serine/threonine protein kinase ark2, putative

PlasmoDB

TDR

In silico prediction of protein targets of antimalarial compounds, suggested target

Prediction of the P. falciparum target space relevant to malaria drug discovery

PF3D7_0312400

PFC0525c

glycogen synthase kinase 3

PlasmoDB

TDR

Picture 1

3,6-diamino-4-(2-bromophenyl)-2-(3,4-dichlorobenzoyl)thieno[2,3-b]pyridine-5-carbonitrile	First report on exploring classification and regression based QSAR modelling of Plasmodium falciparum glycogen synthase kinase (PfGSK-3) inhibitors
3,6-diamino-4-(2-bromophenyl)-2-(3-chlorobenzoyl)thieno[2,3-b]pyridine-5-carbonitrile	First report on exploring classification and regression based QSAR modelling of Plasmodium falciparum glycogen synthase kinase (PfGSK-3) inhibitors
3,6-diamino-4-(2-halophenyl)-2-benzoylthieno[2,3-b]pyridine-5-carbonitriles	3,6-Diamino-4-(2-halophenyl)-2-benzoylthieno[2,3-b]pyridine-5-carbonitriles are selective inhibitors of Plasmodium falciparum glycogen synthase kinase-3
3,6-diamino-4-(thiophen-2-yl)thieno[2,3-b]pyridine-2,5-dicarbonitrile	First report on exploring classification and regression based QSAR modelling of Plasmodium falciparum glycogen synthase kinase (PfGSK-3) inhibitors
3,6-diamino-4-o-tolylthieno[2,3-b]pyridine-2,5-dicarbonitrile	First report on exploring classification and regression based QSAR modelling of Plasmodium falciparum glycogen synthase kinase (PfGSK-3) inhibitors
4-((5-Chloro-4-(5-methylthiophen-2-yl)pyrimidin-2-yl)amino)-N- (3-morpholinopropyl)benzamide (23f)	Identification of Novel 2,4,5-Trisubstituted Pyrimidines as Potent Dual Inhibitors of Plasmodial Pf GSK3/ Pf PK6 with Activity against Blood Stage Parasites In Vitro
4-[(6-methoxy-1-benzofuran-2-yl)carbonyl]benzonitrile	Exploration of benzofuran-based compounds as potent and selective Plasmodium falciparum glycogen synthase kinase-3 (PfGSK-3) inhibitors
4-phenylthieno[2,3-b]pyridine	Structure-activity relationships in a series of antiplasmodial thieno[2,3-b]pyridines
Actinomyces strain FH025	Anti-malarial Activities of Two Soil Actinomycete Isolates from Sabah via Inhibition of Glycogen Synthase Kinase 3ß
Actinomyces strain H11809	Anti-malarial Activities of Two Soil Actinomycete Isolates from Sabah via Inhibition of Glycogen Synthase Kinase 3ß
CHIR 99021	GSK3 inhibitors: development and therapeutic potential
Curcumin	The Antimalarial Effect of Curcumin Is Mediated by the Inhibition of Glycogen Synthase Kinase-3ß
In silico, suggested target	Malarial kinases: novel targets for in silico approaches to drug discovery
indirubin-30-monoxime	Targeting the Ubiquinol-Reduction (Q i) Site of the Mitochondrial Cytochrome bc 1 Complex for the Development of Next Generation Quinolone Antimalarials
Indirubins	Using topological indices to predict anti-Alzheimer and anti-parasitic GSK-3 inhibitors by multi-target QSAR in silico screening
Manzamine a	2-N-Methyl modifications and SAR studies of manzamine A
Meridians	Using topological indices to predict anti-Alzheimer and anti-parasitic GSK-3 inhibitors by multi-target QSAR in silico screening
Paullone	Using topological indices to predict anti-Alzheimer and anti-parasitic GSK-3 inhibitors by multi-target QSAR in silico screening
Quinazolinone	Selective inhibitors of Plasmodium falciparum glycogen synthase-3 (PfGSK-3): New antimalarial agents?
Structure-based design, suggested target	Generation and evaluation of a homology model of PfGSK-3

PF3D7_0420100

PFD0975w

serine/threonine protein kinase RIO2

PlasmoDB

TDR

(1r,2r,3s,5s)-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1] octane-2-carboxylic acid	Skeletal hybridization and PfRIO-2 kinase modeling for synthesis of a-pyrone analogs as anti-malarial agent
8-hydroxy-4-methyl-9-nitro-2h-benzo[g]chromen-2-one	PfRIO-2 kinase is a potential therapeutic target of antimalarial protein kinase inhibitors
Apigenin	PfRIO-2 kinase is a potential therapeutic target of antimalarial protein kinase inhibitors
E-64	PfRIO-2 kinase is a potential therapeutic target of antimalarial protein kinase inhibitors
Ecgonine	Skeletal hybridization and PfRIO-2 kinase modeling for synthesis of a-pyrone analogs as anti-malarial agent
Enzastaurin	PfRIO-2 kinase is a potential therapeutic target of antimalarial protein kinase inhibitors
Ethyl loflazepate	Skeletal hybridization and PfRIO-2 kinase modeling for synthesis of a-pyrone analogs as anti-malarial agent
In silico drug design suggested target	In silico characterization of atypical kinase PFD0975w from Plasmodium kinome: a suitable target for drug discovery
Indirubin-3'-monoxime	PfRIO-2 kinase is a potential therapeutic target of antimalarial protein kinase inhibitors
Kaempferol	PfRIO-2 kinase is a potential therapeutic target of antimalarial protein kinase inhibitors
Ketotifen	Skeletal hybridization and PfRIO-2 kinase modeling for synthesis of a-pyrone analogs as anti-malarial agent
Leupeptin	PfRIO-2 kinase is a potential therapeutic target of antimalarial protein kinase inhibitors
Pepstatin	PfRIO-2 kinase is a potential therapeutic target of antimalarial protein kinase inhibitors
Pfrio2-atp-dna complex formation, suggested target	Molecular and structural insight into plasmodium falciparum RIO2 kinase
Pmsf	PfRIO-2 kinase is a potential therapeutic target of antimalarial protein kinase inhibitors
Wortmannin	PfRIO-2 kinase is a potential therapeutic target of antimalarial protein kinase inhibitors Cloning, Overexpression, Purification and Immunolocal-ization of PFD0975w from the Malaria Parasite Plasmodium falciparum

PF3D7_0424500

PFD1165w

serine/threonine protein kinase, FIKK family

PlasmoDB

TDR

PF3D7_0424700

PFD1175w

serine/threonine protein kinase, FIKK family

PlasmoDB

TDR

PF3D7_0500900

PFE0045c

serine/threonine protein kinase, FIKK family

PlasmoDB

TDR

Picture 1

PF3D7_0525900

PFE1290w

NIMA related kinase 2

PlasmoDB

TDR

Picture 1

4-[(6-ethynyl-9H-purin-2-yl)amino]benzenesulfonamide

A new tool for the chemical genetic investigation of the Plasmodium falciparum Pfnek-2 NIMA-related kinase

PF3D7_0605300

PFF0260w

erine/threonine protein kinase ark1

PlasmoDB

TDR

AZD-1152-HQPA	Chemical signatures and new drug targets for gametocytocidal drug development
Essential suggested target	An essential Aurora-related kinase transiently associates with spindle pole bodies during Plasmodium falciparum erythrocytic schizogony
Hesperadin	Repurposing human Aurora kinase inhibitors as leads for anti-protozoan drug discovery

PF3D7_0704500

MAL7P1.18

serine/threonine protein kinase, putative

PlasmoDB

TDR

PF3D7_0718100

MAL7P1.91

exported serine/threonine protein kinase

PlasmoDB

TDR

Picture 1

PF3D7_0719200

MAL7P1.100

NIMA related kinase 4

PlasmoDB

TDR

PF3D7_0724600

MAL7P1.132

protein kinase, putative

PlasmoDB

TDR

PF3D7_0726200

MAL7P1.144

serine/threonine protein kinase, FIKK family

PlasmoDB

TDR

Picture 1

PF3D7_0731400

MAL7P1.175

serine/threonine protein kinase, FIKK family, pseudogene

PlasmoDB

TDR

PF3D7_0805700

MAL8P1.203

serine/threonine protein kinase, FIKK family

PlasmoDB

TDR

emodin

The anthraquinone emodin inhibits the non-exported FIKK kinase from Plasmodium falciparum

PF3D7_0821100

PF08_0044

protein kinase 1

PlasmoDB

TDR

PF3D7_0902000

PFI0095c

serine/threonine protein kinase, FIKK family

PlasmoDB

TDR

PF3D7_0902100

PFI0100c

serine/threonine protein kinase, FIKK family

PlasmoDB

TDR

Picture 1

PF3D7_0902200

PFI0105c

serine/threonine protein kinase, FIKK family

PlasmoDB

TDR

Picture 1

PF3D7_0902300

PFI0110c

serine/threonine protein kinase, FIKK family

PlasmoDB

TDR

PF3D7_0902400

PFI0115c

serine/threonine protein kinase, FIKK family

PlasmoDB

TDR

Picture 1

PF3D7_0902500

PFI0120c

serine/threonine protein kinase, FIKK family

PlasmoDB

TDR

Picture 1

PF3D7_0902600

PFI0125c

serine/threonine protein kinase, FIKK family

PlasmoDB

TDR

PF3D7_0926300

PFI1285w

protein kinase, putative

PlasmoDB

TDR

PF3D7_0928800

PFI1415w

serine/threonine protein kinase, putative

PlasmoDB

TDR

PF3D7_1016400

PF10_0160

serine/threonine protein kinase, FIKK family

PlasmoDB

TDR

2-[3-[1-[3-[2-[[3-azido-5-(azidomethyl)phenyl]methoxy]ethyl]cyclopenta-1,3-dien-1-yl]ethyl]-4-methyl-thiazol-5-yl]ethanol

A chemical proteomics approach for the search of pharmacological targets of the antimalarial clinical candidate albitiazolium in Plasmodium falciparum using photocrosslinking and click chemistry

PF3D7_1039000

PF10_0380

serine/threonine protein kinase, FIKK family

PlasmoDB

TDR

PF3D7_1103700

PF11_0048

casein kinase II beta chain

PlasmoDB

TDR

Picture 1

Carbazole	Biologically active carbazole derivatives: focus on oxazinocarbazoles and related compounds
Functional analysis, difference from host, suggested target	Functional analysis of protein kinase CK2 of the human malaria parasite Plasmodium falciparum

PF3D7_1108400

PF11_0096

casein kinase 2, alpha subunit

PlasmoDB

TDR

5-(3-chloroanilino)benzo[c][2,6]naphthyridine-8-carboxylic acid	The protein kinase CK2 catalytic domain from Plasmodium falciparum: crystal structure, tyrosine kinase activity and inhibition
Carbazole	Biologically active carbazole derivatives: focus on oxazinocarbazoles and related compounds
Ml-7	Functional analysis of protein kinase CK2 of the human malaria parasite Plasmodium falciparum
Rottlerin	Functional analysis of protein kinase CK2 of the human malaria parasite Plasmodium falciparum

PF3D7_1114700

PF11_0156

cyclin-dependent-like kinase clk3

PlasmoDB

TDR

4-(2-{2-Methoxy-5-[(morpholin-4-yl)methyl]phenyl}-1H-pyrrolo[2,3-b]pyridin-4-yl)-2-(propan-2-yl)benzoic Acid	Development of Potent Pf CLK3 Inhibitors Based on TCMDC-135051 as a New Class of Antimalarials
Altiratinib	Altiratinib blocks Toxoplasma gondii and Plasmodium falciparum development by selectively targeting a spliceosome kinase
Aminopyrimidines	Inhibition of the SR protein-phosphorylating CLK kinases of Plasmodium falciparum impairs blood stage replication and malaria transmission
Oxo-b-carbolines	Inhibition of the SR protein-phosphorylating CLK kinases of Plasmodium falciparum impairs blood stage replication and malaria transmission
TCMDC-135051	Validation of the protein kinase Pf CLK3 as a multistage cross-species malarial drug target

PF3D7_1121900

PF11_0227

3-phosphoinositide-dependent protein kinase 1

PlasmoDB

TDR

PF3D7_1136500

PF11_0377

casein kinase 1

PlasmoDB

TDR

(2R)-2-[[6-(3-chloroanilino)-9-propan-2-ylpurin-2-yl]amino]-3-methylbutan-1-ol	Structure-activity relationships and inhibitory effects of various purine derivatives on the in vitro growth of Plasmodium falciparum
aminopurvalanol	Structure-activity relationships and inhibitory effects of various purine derivatives on the in vitro growth of Plasmodium falciparum
In silico prediction of protein targets of antimalarial compounds, suggested target	Prediction of the P. falciparum target space relevant to malaria drug discovery
isopentenyladenine	Structure-activity relationships and inhibitory effects of various purine derivatives on the in vitro growth of Plasmodium falciparum
methyl-aminopurvalanol	Structure-activity relationships and inhibitory effects of various purine derivatives on the in vitro growth of Plasmodium falciparum
Methyl-purvalanol B	Intracellular targets of cyclin-dependent kinase inhibitors: identification by affinity chromatography using immobilised inhibitors Structure-activity relationships and inhibitory effects of various purine derivatives on the in vitro growth of Plasmodium falciparum
Olomoucine	Structure-activity relationships and inhibitory effects of various purine derivatives on the in vitro growth of Plasmodium falciparum
Purvalanol b	Intracellular targets of cyclin-dependent kinase inhibitors: identification by affinity chromatography using immobilised inhibitors Structure-activity relationships and inhibitory effects of various purine derivatives on the in vitro growth of Plasmodium falciparum
Roscovitine	Intracellular targets of cyclin-dependent kinase inhibitors: identification by affinity chromatography using immobilised inhibitors Structure-activity relationships and inhibitory effects of various purine derivatives on the in vitro growth of Plasmodium falciparum

PF3D7_1145200

PF11_0464

serine/threonine protein kinase, putative

PlasmoDB

TDR

PF3D7_1148000

PF11_0488

serine/threonine protein kinase, putative

PlasmoDB

TDR

BI-2536	Human Polo-like Kinase Inhibitors as Antiplasmodials
In silico prediction of protein targets of antimalarial compounds, suggested target	Prediction of the P. falciparum target space relevant to malaria drug discovery

PF3D7_1149300

PF11_0510

serine/threonine protein kinase, FIKK family

PlasmoDB

TDR

Picture 1

PF3D7_1200800

PFL0040c

serine/threonine protein kinase, FIKK family

PlasmoDB

TDR

Picture 1

PF3D7_1201600

PFL0080c

NIMA related kinase 3

PlasmoDB

TDR

PF3D7_1228300

PFL1370w

NIMA related kinase 1

PlasmoDB

TDR

(2R)-2-[[6-[(3-amino-5-chloro-phenyl)methyl]-9-isopropyl-purin-2-yl]amino]-3-methyl-butan-1-ol	Pfnek-1, a NIMA-related kinase from the human malaria parasite Plasmodium falciparum Biochemical properties and possible involvement in MAPK regulation
Alisiaquinol	Alisiaquinones and alisiaquinol, dual inhibitors of Plasmodium falciparum enzyme targets from a New Caledonian deep water sponge
Alisiaquinone A	Alisiaquinones and alisiaquinol, dual inhibitors of Plasmodium falciparum enzyme targets from a New Caledonian deep water sponge
Alisiaquinone B	Alisiaquinones and alisiaquinol, dual inhibitors of Plasmodium falciparum enzyme targets from a New Caledonian deep water sponge
Alisiaquinone C	Alisiaquinones and alisiaquinol, dual inhibitors of Plasmodium falciparum enzyme targets from a New Caledonian deep water sponge
Drugs not specified, suggeted target	Plasmodium falciparum NIMA-related kinase Pfnek-1: sex specificity and assessment of essentiality for the erythrocytic asexual cycle
Hesperadin	Human Aurora kinase inhibitor Hesperadin reveals epistatic interaction between Plasmodium falciparum PfArk1 and PfNek1 kinases
Hymenialdisine 01	Pfnek-1, a NIMA-related kinase from the human malaria parasite Plasmodium falciparum Biochemical properties and possible involvement in MAPK regulation
Methyl (2,4-dibromo- 3,6-dihydroxyphenyl) acetate	Antiplasmodial activities of homogentisic acid derivative protein kinase inhibitors isolated from a Vanuatu marine sponge Pseudoceratina sp
Purvalanol	Pfnek-1, a NIMA-related kinase from the human malaria parasite Plasmodium falciparum Biochemical properties and possible involvement in MAPK regulation
Roscovitine	Pfnek-1, a NIMA-related kinase from the human malaria parasite Plasmodium falciparum Biochemical properties and possible involvement in MAPK regulation
Xestoquinone	Crystallization and preliminary X-ray analysis of the aspartic protease plasmepsin 4 from the malarial parasite Plasmodium malariae

PF3D7_1230900

PFL1490w

serine/threonine protein kinase RIO1, putative

PlasmoDB

TDR

In silico prediction of protein targets of antimalarial compounds, suggested target

Prediction of the P. falciparum target space relevant to malaria drug discovery

PF3D7_1246900

PFL2250c

RAC-beta serine/threonine protein kinase

PlasmoDB

TDR

Calmodulin, phospholipase c	PfPKB, a protein kinase B-like enzyme from Plasmodium falciparum: II. Identification of calcium/calmodulin as its upstream activator and dissection of a novel signaling pathway
Dihydroartemisinin	A molecular mechanism of artemisinin resistance in Plasmodium falciparum malaria
In silico prediction of protein targets of antimalarial compounds, suggested target	Prediction of the P. falciparum target space relevant to malaria drug discovery

PF3D7_1247500

PFL2280w

serine/threonine protein kinase, putative

PlasmoDB

TDR

In silico prediction of protein targets of antimalarial compounds, suggested target

Prediction of the P. falciparum target space relevant to malaria drug discovery

PF3D7_1338900

MAL13P1.196

serine/threonine protein kinase, putative

PlasmoDB

TDR

PF3D7_1342400

PF13_0232

casein kinase II beta chain

PlasmoDB

TDR

Functional analysis, difference from host, suggested target

Functional analysis of protein kinase CK2 of the human malaria parasite Plasmodium falciparum

PF3D7_1356800

MAL13P1.278

serine/threonine protein kinase ark3, putative

PlasmoDB

TDR

Suggested target

The conserved apicomplexan Aurora kinase TgArk3 is involved in endodyogeny, duplication rate and parasite virulence

PF3D7_1428500

PF14_0264

protein kinase, putative

PlasmoDB

TDR

PF3D7_1433900

PF14_0320

protein kinase, putative

PlasmoDB

TDR

PF3D7_1441300

PF14_0392

serine/threonine protein kinase, putative

PlasmoDB

TDR

PF3D7_1443000

PF14_0408

serine/threonine protein kinase

PlasmoDB

TDR

Aminopyrimidines	Inhibition of the SR protein-phosphorylating CLK kinases of Plasmodium falciparum impairs blood stage replication and malaria transmission
Annomontin	Synthesis of desaza analogues of annomontine and canthin-4-one alkaloids
Oxo-b-carbolines	Inhibition of the SR protein-phosphorylating CLK kinases of Plasmodium falciparum impairs blood stage replication and malaria transmission

PF3D7_1445400

PF14_0431

protein serine/threonine kinase-1

PlasmoDB

TDR

(2R)-2-[[3-[3-[(E)-[(1R)-1-(hydroxymethyl)propyl]iminomethyl]phenyl]imidazo[1,2-b]pyridazin-6-yl]amino]butan-1-ol	Exploration of the imidazo[1,2-b]pyridazine scaffold as a protein kinase inhibitor
Aminopyrimidines	Inhibition of the SR protein-phosphorylating CLK kinases of Plasmodium falciparum impairs blood stage replication and malaria transmission
Annomontin	Synthesis of desaza analogues of annomontine and canthin-4-one alkaloids
Oxo-b-carbolines	Inhibition of the SR protein-phosphorylating CLK kinases of Plasmodium falciparum impairs blood stage replication and malaria transmission

PF3D7_1476400

PF14_0733

serine/threonine protein kinase, FIKK family, pseudogene

PlasmoDB

TDR

Expasy - NiceZime View
Brenda - The Comprehensive Enzyme Information System