You can find more information about 4-hydroxy-3-methylbut-2-enyl diphosphate reductase using the following links:

PFID PFID Old Formal Annotation PlasmoDB TDR Targets Subcellular Localization Affecting Drugs
Drug Name PubMed Articles (year of publication)
PF3D7_0104400 PFA0225w 4-hydroxy-3-methylbut-2-enyl diphosphate reductase PlasmoDB TDR
(e)-4-mercapto-3-methylbut-2-en-1-yl diphosphate
3-methyl-3,4-epoxybutyl diphosphate
5-diphosphomevalonic acid
Competitive inhibition, suggested target
Hammerhead ribozyme
In silico, suggested target
Pyridoxal Diphosphate
Suggested target
Expasy - NiceZime View
Brenda - The Comprehensive Enzyme Information System
Reaction Link