You can find more information about HATs using the following links:

PFID

PFID Old

Formal Annotation

PlasmoDB

TDR Targets

Subcellular Localization

Affecting Drugs

Drug Name

PubMed Articles (year of publication)

PF3D7_0416400

PFD0795w

histone acetyltransferase, putative

PlasmoDB

TDR

(1S,4S,7Z,10S,16E,21R)-7-ethylidene-4,21-di(propan-2-yl)-2-oxa-12,13-dithia-5,8,20,23-tetrazabicyclo[8.7.6]tricos-16-ene-3,6,9,19,22-pentone

Chromobacterium spp. mediate their anti-Plasmodium activity through secretion of the histone deacetylase inhibitor romidepsin

PF3D7_0809500

MAL8P1.114

histone acetyltransferase subunit NuA4, putative

PlasmoDB

TDR

PF3D7_0823300

PF08_0034

histone acetyltransferase GCN5

PlasmoDB

TDR

(2S)-2-[[2-fluoro-4-[(3-methyl-1-oxo-4Hbenzo[f]quinazolin-9-yl) methylamino] benzoyl]amino] pentanedioic acid	Designing novel inhibitors against histone acetyltransferase (HAT: GCN5) of Plasmodium falciparum
2-[[4-[(2-amino-4-oxo-1H-quin azolin-6-yl) methyl-(cyanometh yl)amino]benzoyl]amino] pentnedioic acid(ZINC29250560)	Designing novel inhibitors against histone acetyltransferase (HAT: GCN5) of Plasmodium falciparum
3-chloro-4-methylaniline	Arbitrarily Accessible 3D Microfluidic Device for Combinatorial High-Throughput Drug Screening
6-[4-methyl-2-oxo-5-phenylmet hoxycarbonyl- 6-(4-phenylphen yl)-1,6-dihydropyrimidin-3-yl] hexanoic acid	Designing novel inhibitors against histone acetyltransferase (HAT: GCN5) of Plasmodium falciparum
Anacardic acid	Histone acetyltransferase inhibitor anacardic acid causes changes in global gene expression during in vitro Plasmodium falciparum development
Curcumin	Cytotoxic effect of curcumin on malaria parasite Plasmodium falciparum: inhibition of histone acetylation and generation of reactive oxygen species Synthesis and exploration of novel curcumin analogues as anti-malarial agents Arbitrarily Accessible 3D Microfluidic Device for Combinatorial High-Throughput Drug Screening
fosmidomycin	Histone H3K9 acetylation level modulates gene expression and may affect parasite growth in human malaria parasite Plasmodium falciparum
Hybrid 4-aminoquinoline-1,3,5-triazine	Formulation of nanotized curcumin and demonstration of its antimalarial efficacy
N-[(4-amino-2-methylpyrimidin-5-yl)methyl]-N-[(Z)-5-hydroxy-3-[3-(4-methylphenyl)-3-oxopropyl]sulfanylpent-2-en-2-yl]formamide;hydrochloride	Arbitrarily Accessible 3D Microfluidic Device for Combinatorial High-Throughput Drug Screening
triazolophthalazine	Activity of bromodomain protein inhibitors/binders against asexual-stage Plasmodium falciparum parasites

PF3D7_1020700

PF10_0200

histone acetyltransferase, putative

PlasmoDB

TDR

PF3D7_1118600

PF11_0192

histone acetyltransferase

PlasmoDB

TDR

1,2-Bis(isothiazol-5-yl)disulfane

Inhibition of PfMYST HAT activity blocks Plasmodium falciparum growth and survival

Expasy - NiceZime View
Brenda - The Comprehensive Enzyme Information System