You can find more information about
geranylgeranyl pyrophosphate synthase, putative
using the following links:
PFID
PFID Old
Formal Annotation
PlasmoDB
TDR Targets
Subcellular Localization
Affecting Drugs
Drug Name
PubMed Articles (year of publication)
PF3D7_1128400
PF11_0295
geranylgeranyl pyrophosphate synthase, putative
PlasmoDB
TDR
Picture 1
[2-(3-dodecylimidazol-1-yl)-1-hydroxy-1-phosphono-ethyl]-hydroxy-phosphinate
Dynamic Structure and Inhibition of a Malaria Drug Target: Geranylgeranyl Diphosphate Synthase
Aminomethylene bisphosphonates
Effects of bisphosphonates on the growth of Entamoeba histolytica and Plasmodium species in vitro and in vivo
Bisphosphonate
Bisphosphonates inhibit the growth of Trypanosoma brucei, Trypanosoma cruzi, Leishmania donovani, Toxoplasma gondii, and Plasmodium falciparum: a potential route to chemotherapy
Effects of bisphosphonates on the growth of Entamoeba histolytica and Plasmodium species in vitro and in vivo
Bisquinoline
Pharmacophoric studies of in vitro inhibition of Plasmodium falciparum growth
MMV019313
Specific Inhibition of the Bifunctional Farnesyl/Geranylgeranyl Diphosphate Synthase in Malaria Parasites via a New Small-Molecule Binding Site
N-(2-(2,4-difluorophenyl)thiazol-5-yl)-4-(1,4-oxazepan-4-yl)butanamide
Nonbisphosphonate inhibitors of Plasmodium falciparum FPPS/GGPPS
N-[3-(1-Azepanyl)propyl]-5-methyl-4-oxo-4,5-dihydrothieno[3,2-c]quinoline-2-carboxamide
Using in Vitro Evolution and Whole Genome Analysis To Discover Next Generation Targets for Antimalarial Drug Discovery
Risedronate
Effects of bisphosphonates on the growth of Entamoeba histolytica and Plasmodium species in vitro and in vivo
Lipophilic analogs of zoledronate and risedronate inhibit Plasmodium geranylgeranyl diphosphate synthase (GGPPS) and exhibit potent antimalarial activity
Cloning and characterization of bifunctional enzyme farnesyl diphosphate/geranylgeranyl diphosphate synthase from Plasmodium falciparum
Plasmodium falciparum parasites overexpressing farnesyl diphosphate synthase/geranylgeranyl diphosphate synthase are more resistant to risedronate
Zoledronate
Lipophilic analogs of zoledronate and risedronate inhibit Plasmodium geranylgeranyl diphosphate synthase (GGPPS) and exhibit potent antimalarial activity
Dynamic Structure and Inhibition of a Malaria Drug Target: Geranylgeranyl Diphosphate Synthase
Remarkable similarity in Plasmodium falciparum and Plasmodium vivax geranylgeranyl diphosphate synthase dynamics and its implication for antimalarial drug design
Expasy - NiceZime View
Brenda - The Comprehensive Enzyme Information System
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