You can find more information about
cysteine proteinase falcipain 1
using the following links:
PFID
PFID Old
Formal Annotation
PlasmoDB
TDR Targets
Subcellular Localization
Affecting Drugs
Drug Name
PubMed Articles (year of publication)
PF3D7_1458000
PF14_0553
cysteine proteinase falcipain 1
PlasmoDB
TDR
Picture 1
Picture 2
Picture 3
(ds)RNAs
Double-stranded RNA-mediated gene silencing of cysteine proteases (falcipain-1 and -2) of Plasmodium falciparum
Artemisinin
Haemoglobin degradation underpins the sensitivity of early ring stage Plasmodium falciparum to artemisinins
Dibenzyl aziridine
Blocking effect of a biotinylated protease inhibitor on the egress of Plasmodium falciparum merozoites from infected red blood cells
Dihydroartemisinin
Haemoglobin degradation underpins the sensitivity of early ring stage Plasmodium falciparum to artemisinins
E-64
Falcipain-1, a Plasmodium falciparum cysteine protease with vaccine potential
E64d
Haemoglobin degradation underpins the sensitivity of early ring stage Plasmodium falciparum to artemisinins
Leupeptin
Falcipain-1, a Plasmodium falciparum cysteine protease with vaccine potential
N-acetyl-Leu-Leu-norLeu
Haemoglobin degradation underpins the sensitivity of early ring stage Plasmodium falciparum to artemisinins
Haemoglobin degradation underpins the sensitivity of early ring stage Plasmodium falciparum to artemisinins
Peptidyl epoxides
A role for the protease falcipain 1 in host cell invasion by the human malaria parasite
RNAi
Double-stranded RNA-mediated gene silencing of cysteine proteases (falcipain-1 and -2) of Plasmodium falciparum
Suggested target
The in-vitro antimalarial activity of ferrochloroquine, measured against Cambodian isolates of Plasmodium falciparum
Symplostatin
The antimalarial natural product symplostatin 4 is a nanomolar inhibitor of the food vacuole falcipains
Tcmdc-135965
Thousands of chemical starting points for antimalarial lead identification
Ya29
Plasmodium falciparum cysteine protease falcipain-1 is not essential in erythrocytic stage malaria parasites
Expasy - NiceZime View
Brenda - The Comprehensive Enzyme Information System