You can find more information about DNA gyrase subunit A using the following links:

Subcellular Localization

• Picture 1

Affecting Drugs
Drug Name	PubMed Articles (year of publication)
3,6-diamino-10- methylacridinum chloride	Potent antimalarial activity of acriflavine in vitro and in vivo(2014)
3,6-diaminoacridine	Potent antimalarial activity of acriflavine in vitro and in vivo(2014)
Biochemical analyses, suggested target	Investigating the Roles of the C-Terminal Domain of Plasmodium falciparum GyrA(2015)
ciprofloxacin	Nuclear gyrB encodes a functional subunit of the Plasmodium falciparum gyrase that is involved in apicoplast DNA replication(2007) Enhancement of the antimalarial activity of ciprofloxacin using a double prodrug/bioorganometallic approach(2009) Targeting the gyrase of Plasmodium falciparum with topoisomerase poisons(2015) Validation of Putative Apicoplast-Targeting Drugs Using a Chemical Supplementation Assay in Cultured Human Malaria Parasites(2017)
ethyl 1-cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-yl-quinoline-3-carboxylate	Enhancement of the antimalarial activity of ciprofloxacin using a double prodrug/bioorganometallic approach(2009)
ethyl 1-cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-yl-quinoline-3-carboxylate;ferrocene	Enhancement of the antimalarial activity of ciprofloxacin using a double prodrug/bioorganometallic approach(2009)
ethyl 6-fluoro-1-methyl-4-oxo-7-piperazin-1-yl-quinoline-3-carboxylate;ferrocene	Enhancement of the antimalarial activity of ciprofloxacin using a double prodrug/bioorganometallic approach(2009)
etoposide	Targeting the gyrase of Plasmodium falciparum with topoisomerase poisons(2015)
Fluoroquinolone	Enhancement of the antimalarial activity of ciprofloxacin using a double prodrug/bioorganometallic approach(2009)
Quinolone	A systematic in silico search for target similarity identifies several approved drugs with potential activity against the Plasmodium falciparum apicoplast(2013)
Ribozyme rz491gyra	Ribozyme cleavage of Plasmodium falciparum gyrase A gene transcript affects the parasite growth(2008)
Suggested target	Molecular cloning of apicoplast-targeted Plasmodium falciparum DNA gyrase genes: unique intrinsic ATPase activity and ATP-independent dimerization of PfGyrB subunit(2007)
Tcmdc-134527	Thousands of chemical starting points for antimalarial lead identification(2010)