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Subcellular Localization

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Affecting Drugs
Drug Name	PubMed Articles (year of publication)
1,2,3-trihydroxybenzene	Structural characterization and inhibition of the Plasmodium Atg8-Atg3 interaction(2012)
1-[(3-methylphenyl)methyl]-3-{[1-(pyridin-2-ylmethyl)pyrrolidin-3-yl]methyl}urea	Virtual Screening and Experimental Validation Identify Novel Inhibitors of the Plasmodium falciparum Atg8-Atg3 Protein-Protein Interaction(2016)
2-bromo-N-(4 -pyridin-2- yl-1,3-thiazo l-2-yl)benzamide	Biological functions and structural biology of Plasmodium falciparum autophagy-related proteins: the under-explored options for novel antimalarial drug design(2023)
3-Methyladenine	Characterization of the autophagy marker protein Atg8 reveals atypical features of autophagy in Plasmodium falciparum(2014)
4-pyridin-2-yl-1,3-thiazol-2-amine	Identification of an Atg8-Atg3 protein-protein interaction inhibitor from the medicines for Malaria Venture Malaria Box active in blood and liver stage Plasmodium falciparum parasites(2014)
Chloroquine	Characterization of the autophagy marker protein Atg8 reveals atypical features of autophagy in Plasmodium falciparum(2014)
E64	Characterization of the autophagy marker protein Atg8 reveals atypical features of autophagy in Plasmodium falciparum(2014)
Pepstatin	Characterization of the autophagy marker protein Atg8 reveals atypical features of autophagy in Plasmodium falciparum(2014)