You can find more information about
PF3D7_1246100-5-aminolevulinate synthase
using the following links:
PlasmoDB - the Plasmodium genome resource
The TDR Targets Database
Subcellular Localization
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Affecting Drugs
Drug Name
PubMed Articles (year of publication)
Essentiality, suggested target
Import of host delta-aminolevulinate dehydratase into the malarial parasite: identification of a new drug target(2000)
Ethanolamine
Involvement of delta-aminolaevulinate synthase encoded by the parasite gene in de novo haem synthesis by Plasmodium falciparum(2002)
Metabolic network analysis, suggested target
Antimalarial drug targets in Plasmodium falciparum predicted by stage-specific metabolic network analysis(2010)
Succinylacetone
de novo biosynthesis of heme offers a new chemotherapeutic target in the human malarial parasite(1992)