You can find more information about
PF3D7_1344800-Aspartate carbamoyltransferase
using the following links:
PlasmoDB - the Plasmodium genome resource
The TDR Targets Database
Subcellular Localization
Picture 1
PDB protein strucure
6HL7
5ILQ
6FBA
5ILN
Affecting Drugs
Drug Name
PubMed Articles (year of publication)
2,3- napthalenediol
Identification of a non-competitive inhibitor of Plasmodium falciparum aspartate transcarbamoylase(2018)
2-amino-N-(2-methoxyethyl)-5-phenylthiophene-3-carboxamide
Discovery of Small-Molecule Allosteric Inhibitors of Pf ATC as Antimalarials(2022)
Crystal structure
Crystal structure of truncated aspartate transcarbamoylase from Plasmodium falciparum(2016)
Crystal structure suggested target
Crystal structure of truncated aspartate transcarbamoylase from Plasmodium falciparum(2016)
N-phosphonacetyl-L-aspartate
Novel Highlight in Malarial Drug Discovery: Aspartate Transcarbamoylase(2022)
Torin 1
Chemical signatures and new drug targets for gametocytocidal drug development(2014)
Torin 2
Molecular Target Validation of Aspartate Transcarbamoylase from Plasmodium falciparum by Torin 2(2020)