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Subcellular Localization

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PDB protein strucure

• 1A5C
• 2EPH
• 2PC4
• 4TR9

Affecting Drugs
Drug Name	PubMed Articles (year of publication)
3,4-dihydroxy-N'-(2-hydroxybenzylidene)benzohydrazide	Inhibition by stabilization: targeting the Plasmodium falciparum aldolase-TRAP complex(2015)
Arthemeter	Towards a proteomic definition of CoArtem action in Plasmodium falciparum malaria(2005)
Bisindolemaleimide iii	Identification of potential multitarget antimalarial drugs(2005)
Chloroquine	Chloroquine mediates specific proteome oxidative damage across the erythrocytic cycle of resistant Plasmodium falciparum(2008)
Doxycycline	Plasmodium falciparum proteome changes in response to doxycycline treatment(2010)
N'-(2,4-dichlorobenzylidene)-3,4-dihydroxybenzohydrazide	Inhibition by stabilization: targeting the Plasmodium falciparum aldolase-TRAP complex(2015)
N'-(5-chloro-2-hydroxybenzylidene)-4-hydroxy-3-methoxybenzohydrazide	Inhibition by stabilization: targeting the Plasmodium falciparum aldolase-TRAP complex(2015)
N-(benzylideneamino)benzamide	Inhibition by stabilization: targeting the Plasmodium falciparum aldolase-TRAP complex(2015)
Phosphorothioate	Antimalarial drug targets in Plasmodium falciparum predicted by stage-specific metabolic network analysis(2010)
Phosphorothioate antisense	Antisense oligonucleotides targeting malarial aldolase inhibit the asexual erythrocytic stages of Plasmodium falciparum(1999)
Remiszewski_013	Identification of potential multitarget antimalarial drugs(2005)
Suggested target	A conserved molecular motor drives cell invasion and gliding motility across malaria life cycle stages and other apicomplexan parasites(2006)
Telomerase inhibitor v	Identification of potential multitarget antimalarial drugs(2005)