You can find more information about serine hydroxymethyltransferase using the following links:

PlasmoDB - the Plasmodium genome resource
The TDR Targets Database

Subcellular Localization

PDB protein strucure

Affecting Drugs
Drug Name PubMed Articles (year of publication)
(±)-(1-{3-[6-Amino-5-cyano-3-methyl-4-isopropyl-2,4-dihydropyrano[2,3-c]pyrazol-4-yl]-5- fluorophenyl}piperidin-4-yl)acetic Acid
(±)-6-Amino-3-methyl-4-isopropyl-4-[3-(pyridin-4-yl)-5-(trifluoromethyl)phenyl]-2,4- dihydropyrano[2,3-c]pyrazole-5-carbonitrile
(±)-Methyl 5-[3-(6-Amino-5-cyano-4- isopropyl-3-methyl-1,4-dihydropyrano[2,3-c]pyrazol-4-yl)-5-cyanophenyl]thiophene-2-carboxylate
(±)-Methyl 5-[3-(6-Amino-5-cyano-4-isopropyl-3-methyl-1,4-dihydropyrano[2,3-c]pyrazol-4-yl)-5-cyanophenyl]-thiophene-2-carboxylate
[2-[3-(5-benzyloxycarbonyl-2-thienyl)-5-cyano-phenyl]-4-[hydroxy(methyl)amino]-4-oxo-butyl]phosphonic acid
6'-amino-4-fluoro-2,2,3'-trimethyl-6-(pyridin-4-yl)-2,3-dihydro-2'H-spiro[indene-1,4'-pyrano[2,3-c]pyrazole]-5'-carbonitrile
Cinnamic acid
Novel disulfide/sulfhydryl switch , suggested target
Phosphonomethoxyethyl
Pyrazolopyran
Suggested target