You can find more information about
threonine--tRNA ligase
using the following links:
PlasmoDB - the Plasmodium genome resource
The TDR Targets Database
Subcellular Localization
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Affecting Drugs
Drug Name
PubMed Articles (year of publication)
Borrelidin
A unique hydrophobic cluster near the active site contributes to differences in borrelidin inhibition among threonyl-tRNA synthetases(2005)
Antimalarial drug targets in Plasmodium falciparum predicted by stage-specific metabolic network analysis(2010)
Using in Vitro Evolution and Whole Genome Analysis To Discover Next Generation Targets for Antimalarial Drug Discovery(2018)
Bufexamac
Analogs of natural aminoacyl-tRNA synthetase inhibitors clear malaria in vivo(2014)
Chloroquine
Structural basis for full-spectrum inhibition of translational functions on a tRNA synthetase(2015)