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Subcellular Localization

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Affecting Drugs
Drug Name	PubMed Articles (year of publication)
2,5-diaminobenzophenone	Antimalarial and antitrypanosomal activity of a series of amide and sulfonamide derivatives of a 2,5-diaminobenzophenone(2009)
ACT-451840	CRISPR-Cas9-modified pfmdr1 protects Plasmodium falciparum asexual blood stages and gametocytes against a class of piperazine-containing compounds but potentiates artemisinin-based combination therapy partner drugs(2016)
amaranth	The Potential of Secondary Metabolites from Plants as Drugs or Leads against Protozoan Neglected Diseases-Part III: In-Silico Molecular Docking Investigations.(2016)
carmoisine	The Potential of Secondary Metabolites from Plants as Drugs or Leads against Protozoan Neglected Diseases-Part III: In-Silico Molecular Docking Investigations.(2016)
Chembl2387271	UV-triggered affinity capture identifies interactions between the Plasmodium falciparum multidrug resistance protein 1 (PfMDR1) and antimalarial agents in live parasitized cells(2013)
Chloroquine	Purified Plasmodium falciparum multi-drug resistance protein (PfMDR 1) binds a high affinity chloroquine analogue(2010) PfMDR1: mechanisms of transport modulation by functional polymorphisms(2011) Monitoring PfMDR1 transport in Plasmodium falciparum(2015)
Chlorpheniramine	Chemosensitization potential of P-glycoprotein inhibitors in malaria parasites(2013)
Cyclosporin a	Genetic linkage of pfmdr1 with food vacuolar solute import in Plasmodium falciparum(2006)
cyclosporin A	Influence of the Plasmodium falciparum P-glycoprotein homologue 1 (pfmdr1 gene product) on the antimalarial action of cyclosporin(2007)
Dihydroartemisinin	Monitoring PfMDR1 transport in Plasmodium falciparum(2015)
Doxycycline	PftetQ and pfmdt copy numbers as predictive molecular markers of decreased ex vivo doxycycline susceptibility in imported Plasmodium falciparum malaria(2013)
Mefloquine	Purified Plasmodium falciparum multi-drug resistance protein (PfMDR 1) binds a high affinity chloroquine analogue(2010) PfMDR1: mechanisms of transport modulation by functional polymorphisms(2011) Monitoring PfMDR1 transport in Plasmodium falciparum(2015)
Mk571	A 2-amino quinoline, 5-(3-(2-(7-chloroquinolin-2-yl)ethenyl)phenyl)-8-dimethylcarbamyl-4,6-dithiaoctanoic acid, interacts with PfMDR1 and inhibits its drug transport in Plasmodium falciparum(2014)
Ont-093	Genetic linkage of pfmdr1 with food vacuolar solute import in Plasmodium falciparum(2006)
P-loop ntpase, no human ortholog, suggested target	A systematic classification of Plasmodium falciparum P-loop NTPases: structural and functional correlation(2009)
polycyclic amines	Polycyclic amines as chloroquine resistance modulating agents in Plasmodium falciparum(2016)
Quinacrine	Monitoring PfMDR1 transport in Plasmodium falciparum(2015)
Quinine	Purified Plasmodium falciparum multi-drug resistance protein (PfMDR 1) binds a high affinity chloroquine analogue(2010) PfMDR1: mechanisms of transport modulation by functional polymorphisms(2011) Monitoring PfMDR1 transport in Plasmodium falciparum(2015)
tartazine	The Potential of Secondary Metabolites from Plants as Drugs or Leads against Protozoan Neglected Diseases-Part III: In-Silico Molecular Docking Investigations.(2016)
Verapamil	Genetic linkage of pfmdr1 with food vacuolar solute import in Plasmodium falciparum(2006) Monitoring PfMDR1 transport in Plasmodium falciparum(2015)
Xr-9576	Genetic linkage of pfmdr1 with food vacuolar solute import in Plasmodium falciparum(2006)