You can find more information about PF3D7_0923800-thioredoxin reductase using the following links:

PlasmoDB - the Plasmodium genome resource
The TDR Targets Database

Subcellular Localization

PDB protein strucure

Affecting Drugs
Drug Name PubMed Articles (year of publication)
(2aS*,3R*,4aS*,6R*)-1-Benzyl-6-hydroxy-3-tridecyl-2a,3,5,6- tetrahydro-1H-benzofuro[3a,3-b]azet-2(4aH)-one
[5-[[3-(4-methylpiperazine-1-carbonyl)-4-nitro-phenyl]disulfanyl]-2-nitro-phenyl]-(4-methylpiperazin-1-yl)methanone
1-(Ethanesulfonyl)piperidin-4-one
1,4-bis(3-aminopropyl)piperazine
1-Benzyl-3-tetradecanoyl-1-azaspiro[3.5]nona-5,8-diene-2,7- dione
2-(2-methoxyanilino)-3-piperidin-1-ylnaphthalene-1,4-dione
2,1,3-benzothiadiazole
2,4-dinitro-1-(4-nitrophenyl)sulfanyl-benzene
2-Benzyl-4-tetradecanoyl-2-azaspiro[4.5]deca-6,9-diene-3,8- dione
2-chloro-1,3-dinitro-5-(trifluoromethyl)benzene
2-ethyl-1,3-dimethylquinolin-4-imine;hydroiodide
3-ethyl-1-methyl-2-propylquinolin-4-imine;hydron;iodide
4-nitro-2,1,3-benzothiadiazole
4-nitrobenzothiadiazole
5-chloro-4-(6,7-diethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl)-2-methoxyphenol
6,7-dinitroquinoxaline
7-amino-3-(3,4-dimethoxyphenyl)-2-methylpyrazolo[1,5-a]pyrimidine-6-carbonitrile
Aculeatin a
a-methylene artemisone
Aminopyrazole
Araplysillin i
Artemisinin
Artemisone
Auranofin
Aurothiomalate
Biochemical characterization, suggested target
Bis-2,4-dinitrophenyl sulfide
b-methylene artemisone
C3361
Catharanthine
Compounds 1- 4, structures in article
Crystal structure, f2 609–1801 and f2 609–2095
Crystal structure, suggested target
Cubein
cyclam
Dextran sulphate 500
Doxycycline
Eosin b
Essential enzyme, suggested target
Ferriprotoporphyrin ix
L-buthionine sulfoximine
N-[3-(dimethylamino)propyl]-5-[[3-[3-(dimethylamino)propylcarbamoyl]-4-nitro-phenyl]disulfanyl]-2-nitro-benzamide;hydrogen sulfide
Nitrophenyl derivatives
Nitroquinoxaline
O-methyl-2-adamantanone oxime
Pentosan polysulfate
Polymyxin b
Quinacrine
Quinine
Rolitetracycline
Tcmdc-124315
Tcmdc-124316
Tcmdc-125149
Tcmdc-135234
Tcmdc-135585
Tcmdc-135596
Tcmdc-135609
Tetracycline
Unsaturated and saturated mannich bases