You can find more information about PF3D7_0925700-histone deacetylase using the following links:

PlasmoDB - the Plasmodium genome resource
The TDR Targets Database

Subcellular Localization

Affecting Drugs
Drug Name PubMed Articles (year of publication)
(2R)-N-[(1S)-7-(hydroxyamino)-1-(m-tolylcarbamoyl)-7-oxo-heptyl]-5-oxo-pyrrolidine-2-carboxamide
(2R)-N-[(1S)-7-(hydroxyamino)-7-oxo-1-[[3-(trifluoromethyl)phenyl]carbamoyl] heptyl]-5-oxo-pyrrolidine-2-carboxamide
(2S)-N-[(1S)-7-(hydroxyamino)- 7-oxo-1-(phenylcarbamoyl)heptyl]-4-oxo-azetidine-2-carboxamide
(3S,6S,9S)-6-(1-methoxy-4-oxo-3-quinolyl)-9-(6-oxooctyl)-3-sec-butyl-1,4,7,10-tetrazabicyclo[10.4.0]hexadecane-2,5,8,11-tetrone
(3S,6S,9S)-6-(1-oxo-4H-naphthalen-2-yl)-9-(6-oxooctyl)-3-sec-butyl-1,4,7,10-tetrazabicyclo[10.4.0]hexadecane-2,5,8,11-tetrone
(3S,6S,9S)-6-(4-methoxy-1-oxo-4H-naphthalen-2-yl)-9-(6-oxooctyl)-3-sec-butyl-1,4,7,10-tetrazabicyclo[10.4.0]hexadecane-2,5,8,11-tetrone
(3S,6S,9S)-6-(4-methoxy-1-oxo-4H-naphthalen-2-yl)-9-[6-(oxiran-2-yl)-6-oxo-hexyl]-3-sec-butyl-1,4,7,10-tetrazabicyclo[10.4.0]hexadecane-2,5,8,11-tetrone
(3S,6S,9S)-6-[(1-methylindol-3-yl)methyl]-9-(6-oxooctyl)-3-sec-butyl-1,4,7,10-tetrazabicyclo[10.4.0]hexadecane-2,5,8,11-tetrone
(3S,6S,9S)-6-[(2-bromo-1H-indol-3-yl)methyl]-9-(6-oxooctyl)-3-sec-butyl-1,4,7,10-tetrazabicyclo[10.4.0]hexadecane-2,5,8,11-tetrone
(3S,6S,9S)-9-(6-oxooctyl)-6-[[1-(pyrrolidin-1-ylmethyl)indol-3-yl]methyl]-3-sec-butyl-1,4,7,10-tetrazabicyclo[10.4.0]hexadecane-2,5,8,11-tetrone
(3S,6S,9S)-9-(7-fluoro-6-oxo-octyl)-6-(4-methoxy-1-oxo-4H-naphthalen-2-yl)-3-sec-butyl-1,4,7,10-tetrazabicyclo[10.4.0]hexadecane-2,5,8,11-tetrone
(3S,6S,9S)-9-(7-hydroxy-6-oxo-octyl)-6-(4-methoxy-1-oxo-4H-naphthalen-2-yl)-3-sec-butyl-1,4,7,10-tetrazabicyclo[10.4.0]hexadecane-2,5,8,11-tetrone
(3S,6S,9S,12S)-3-Benzyl-6-methyl-9-[6-(oxiran-2-yl)-6-oxohexyl]-1,4,7,10-tetrazabicyclo[10.3.0]pentadecane-2,5,8,11-tetrone
(bis)alkylpolyamines
(E)-N-(2-Aminophenyl)-3-(4-((((3R,5aS,6R,8aS,9R,12R,12aR)-3,6,9-trimethyldecahydro12H-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-yl)oxy)methyl)phenyl)acrylamide
(S)-2-cinnamamido-N8-hydroxy-N1-(quinolin-8-yl)octanediamid
(S)-N8-hydroxy-2-(1H-indole-2-carboxamido)-N1-(quinolin-8-yl)octanediamide
[3’-keto-MeBmt] cyclosporin D
1-[3′-N-(N′-phenylurenyl)phenyl]- 3(3,4,5-trimethoxyphenyl)-2-propen-1-one
2-(2-((6-cyano-1-methyl-1H-indol-3-yl)methyl)-2,6-diazaspiro[3.4]octan-6-yl)-N-hydroxypyrimidine-5-carboxamide
2-(7-((5-cyano-1-methyl-1H-indol-3-yl)methyl)-2,7-diazaspiro[4.4]nonan-2-yl)-N-hydroxypyrimidine-5-carboxamide
2-aminosuberic acid
2-ASA-9
2-asa-9, wr301801
3-(4-bromophenyl)-1-(4-hydroxybutylamino)-2- phenylheptan-3-ol
5-azacytidine
6-[(1-Benzothiophen-2-ylformamido)oxy]-N-hydroxyhexanamide
6-[(3S,6S,9S)-6-(4-methoxy-1-oxo-4H-naphthalen-2-yl)-2,5,8,11-tetraoxo-3-sec-butyl-1,4,7,10-tetrazabicyclo[10.4.0]hexadecan-9-yl]hexanehydroxamic acid
Alkoxyamide
Apicidin
apicidin 1A
Apicidin A
Apicidin f
Aroyl-pyrrolyl-hydroxyamide
Aryltriazolylhydroxamates
Azelaic acid
azelaic bishydroxamic acid
Cay10603
Chembl181459
Cherry-picked hits from the hdac-biased chemical library
Cinnamic acid
dsRNA
dynasore
Hmba
Hydroxamic acid
Ketolide
LMK235
Methyl 4-({[5-(hydroxycarbamoyl)pentyl]oxy}carbamoyl)-benzoate
MS-275
N-(2-(Cyclohexylamino)-2-oxoethyl)-N-(4-(hydrox-ycarbamoyl)benzyl)-2,4-dimethylbenzamide
N-(2-(Cyclohexylamino)-2-oxoethyl)-N-(4-(hydroxycarbamoyl)benzyl)-4-isopropylbenzamide
N-(2,5-dimethylphenoxy)-4-(hydroxycarbamoyl)benzamide
N-(4-(2-(Diethylamino)ethylcarbamoyl)phenyl)-N8 -hydroxyoctanediamide
N-[4-(3-amino-4-methoxyphenyl)-1,3-thiazol-2-yl]-N'-hydroxyoctanediamide
N1-(4-((4-((1-(4-Fluorobenzyl)piperidin-4-yl)amino)-6,7-dimethoxyquinazolin-2-yl)amino)phenyl)-N8-hydroxyoctanediamide hydrochloride
N-hydroxy-2-(4-((((1-methyl-1H-indol-3-yl)methyl)amino)methyl)piperidin-1-yl)pyrimidine-5-carboxamide
N-hydroxy-4-((4-(4-(pyrrolidin-1-ylmethyl)phenyl)-1H-1,2,3-triazol-1-yl)methyl)benzamide
N-hydroxy-4-(3-methyl-2-phenylbutanamido)benzamide
Nonpeptide macrocyclic
Panobinostat
Proteins predicted to be involved in cell cycle regulatory network
Romidepsin
Saha
SAHA(E)-3-{2-butyl-1-[2-(diethylamino) ethyl]benzimidazol-5-yl}prop-2-ene hydroxamic acid
Salicylhydroxamic acid
Santacruzamate a
Sb939
SBHA
SHA
Sirtinol
Suberic acid
Suberoylanilide
Suberoylanilide hydroxamic acid
Suberoylanilide hydroxamic acid
suberylanilide hydroxamic acid
Triazolylphenyl
Trichostatin
Trichostatin a
tubacin
Tyrocidine b
Verlindamycin
Vorinostat
WR301801
WR301839
WR301858
WR308292