You can find more information about PF3D7_1224000-GTP cyclohydrolase using the following links:

PlasmoDB - the Plasmodium genome resource
The TDR Targets Database
Affecting Drugs
Drug Name PubMed Articles (year of publication)
6- (phenylhydrazino)uracil, s 6-(p-n-heptylanilino)uracil
8-oxo-GTP
Gene amplification
increased copy number
Protein expression, suggested target