You can find more information about PF3D7_1247400-PPI using the following links:

Subcellular Localization

• Picture 1
• Picture 2
• Picture 3

PDB protein strucure

• 2FBN
• 2VN1
• 4QT2
• 4QT3
• 2OFN

Affecting Drugs
Drug Name	PubMed Articles (year of publication)
(1S,5S,6R)-10-((3,5-Dichlorophenyl)sulfonyl)-5- ethyl-3-(pyridin-2-ylmethyl)-3,10-diazabicyclo[4.3.1]decan-2-one.	Structural insights into Plasmodium PPIases(2022)
(R)-3-(3,4-dimethoxyphenyl)-1-phenylpropyl (S)-1-(3,3-dimethyl-2-oxopentanoyl)piperidine-2-carboxylate	Targeted Covalent Inhibition of Plasmodium FK506 Binding Protein 35(2020)
13-dM(Me)-18-OH-Fk520	Molecular docking study of macrocycles as Fk506-binding protein inhibitors(2015)
13-dM(Me)-Fk520	Molecular docking study of macrocycles as Fk506-binding protein inhibitors(2015)
18-OH-FK520	Molecular docking study of macrocycles as Fk506-binding protein inhibitors(2015)
2-bromo-3-methyl-1,4-dimethoxy-9,10-anthraquinone	Molecular docking study of macrocycles as Fk506-binding protein inhibitors(2015)
4'-sub-1,2,3,4-tetrahydrorapamycin	Molecular docking study of macrocycles as Fk506-binding protein inhibitors(2015)
Ascomycin	The FK506-binding protein of the malaria parasite, Plasmodium falciparum, is a FK506-sensitive chaperone with FK506-independent calcineurin-inhibitory activity(2005)
Carbocyclic thymidine	Targeting FK506 binding proteins to fight malarial and bacterial infections: current advances and future perspectives(2011)
Cyclosporin a	A Plasmodium falciparum FK506-binding protein (FKBP) with peptidyl-prolyl cis-trans isomerase and chaperone activities(2005)
cyclosporin A	Immunophilin-protein interactions in Plasmodium falciparum(2015)
D44	Structural insights into Plasmodium PPIases(2022)
Desmethoxyrapamycin	Molecular docking study of macrocycles as Fk506-binding protein inhibitors(2015)
Desmethylrapamycin	Molecular docking study of macrocycles as Fk506-binding protein inhibitors(2015)
Fk506	A Plasmodium falciparum FK506-binding protein (FKBP) with peptidyl-prolyl cis-trans isomerase and chaperone activities(2005) Molecular docking study of macrocycles as Fk506-binding protein inhibitors(2015) Immunophilin-protein interactions in Plasmodium falciparum(2015) The antimalarial action of FK506 and rapamycin: evidence for a direct effect on FK506-binding protein PfFKBP35(2017) Structural insights into Plasmodium PPIases(2022)
Fk506	Expression, purification, and molecular characterization of Plasmodium falciparum FK506-binding protein 35 (PfFKBP35)(2007) Crystal structure of the FK506 binding domain of Plasmodium falciparum FKBP35 in complex with FK506(2008) 1H, 13C, and 15N resonance assignments of FK506-binding domain of Plasmodium falciparum FKBP35(2007) Molecular docking study of macrocycles as Fk506-binding protein inhibitors(2015)
Fk520	Antimalarial effects of macrolactones related to FK520 (ascomycin) are independent of the immunosuppressive properties of the compounds(2005) Molecular docking study of macrocycles as Fk506-binding protein inhibitors(2015)
Ils-920	Molecular docking study of macrocycles as Fk506-binding protein inhibitors(2015)
Imidazopyrazines	Crystal structure of Plasmodium vivax FK506-binding protein 25 reveals conformational changes responsible for its noncanonical activity(2014)
immunomycin derivative	Molecular docking study of macrocycles as Fk506-binding protein inhibitors(2015)
Kdu691	Crystal structure of Plasmodium vivax FK506-binding protein 25 reveals conformational changes responsible for its noncanonical activity(2014)
N-(2-ethyl-phenyl)-2-(3h-imidazao [4, 5-b] pyridin-2-yl-sulfanyl)-acetamide	Small molecule Plasmodium FKBP35 inhibitor as a potential antimalaria agent(2013)
Prolylrapamycin	Molecular docking study of macrocycles as Fk506-binding protein inhibitors(2015)
Quinolone	A Plasmodium falciparum FK506-binding protein (FKBP) with peptidyl-prolyl cis-trans isomerase and chaperone activities(2005)
rapamycin	The FK506-binding protein of the malaria parasite, Plasmodium falciparum, is a FK506-sensitive chaperone with FK506-independent calcineurin-inhibitory activity(2005) Molecular docking study of macrocycles as Fk506-binding protein inhibitors(2015) Two crystal structures of the FK506-binding domain of Plasmodium falciparum FKBP35 in complex with rapamycin at high resolution(2015) The antimalarial action of FK506 and rapamycin: evidence for a direct effect on FK506-binding protein PfFKBP35(2017) Structural insights into Plasmodium PPIases(2022)
Suggested target	Crystal structure of Plasmodium vivax FK506-binding protein 25 reveals conformational changes responsible for its noncanonical activity(2014)
Tacrolimus	Computational insights into the suicide inhibition of Plasmodium falciparum Fk506-binding protein 35(2015)
Way-179639	Molecular docking study of macrocycles as Fk506-binding protein inhibitors(2015)
Wye-592	Molecular docking study of macrocycles as Fk506-binding protein inhibitors(2015)