You can find more information about
PF3D7_1411400-PREX
using the following links:
PlasmoDB - the Plasmodium genome resource
The TDR Targets Database
Subcellular Localization
Picture 1
Picture 2
PDB protein strucure
5DKT
5DKU
Affecting Drugs
Drug Name
PubMed Articles (year of publication)
Daunorubicin
Helicases - feasible antimalarial drug target for Plasmodium falciparum(2007)
KU0263501
Discovery of small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase(2022)
MMV666123
Crystal Structure of the Apicoplast DNA Polymerase from Plasmodium falciparum: The First Look at a Plastidic A-Family DNA Polymerase(2016)
Nogalamycin
Helicases - feasible antimalarial drug target for Plasmodium falciparum(2007)
X-ray diffraction, suggested target
Crystallization and preliminary X-ray analysis of the Plasmodium falciparum apicoplast DNA polymerase(2015)