ARO is late transcribed in blood stages of P. falciparum and co-localizes with the rhoptries.. C) Immunofluorescence of glutaraldehyde/formaldehyde fixed wild type parasites using anti-PfARO antibodies (green) on schizont (s) and merozoite (m) stage parasites. Co-localization of PfARO with (D) the rhoptry marker RALP-1 (red) and (E) the microneme marker EBA-181 (red). Nuclei stained with DAPI (blue). Enlargement of selected areas are marked with white square and referred as Zoom. Scale bar, 1 μm. Cabrera A, Herrmann S, Warszta D, Santos JM, John Peter AT, Kono M, Debrouver S, Jacobs T, Spielmann T, Ungermann C, Soldati-Favre D, Gilberger TW. Dissection of minimal sequence requirements for rhoptry membrane targeting in the malaria parasite. Traffic. 2012 Oct;13(10):1335-50. PMID: 22759070.

r Code