IFM images of fixed 3D7 parasites expressing full-length ALAD tagged at its endogenous locus with C-terminal GFP confirm targeting to the parasite apicoplast.
Parasites were stained with αGFP and αACP (ACP, apicoplast marker).
Sigala PA, Crowley JR, Henderson JP, Goldberg DE. Deconvoluting heme biosynthesis to target blood-stage malaria parasites. Elife. 2015 Jul 14;4. PMID: 26173178.
Other associated proteins
PFID | Formal Annotation |
---|---|
PF3D7_1440300 | delta-aminolevulinic acid dehydratase porphobilinogen synthase, HemB |