Localization of 7-Helix-1 in stress granules (SGs) and interaction with translational repressors. Co-localization of 7-Helix-1 with CITH, PABP1 and DOZI (development of zygote inhibited). WT NF54 gametocytes were immunolabeled with mouse anti-7-Helix-1rp2 antisera (green) and rabbit anti-CITH, anti-PABP1, or anti-DOZI antibodies (red). Nuclei were highlighted by Hoechst33342 nuclear stain (blue). DIC, differential interference contrast. Bar, 5 μm. Results are representative of three independent experiments. Bennink S, von Bohl A, Ngwa CJ, Henschel L, Kuehn A, Pilch N, Weißbach T, Rosinski AN, Scheuermayer M, Repnik U, Przyborski JM, Minns AM, Orchard LM, Griffiths G, Lindner SE, Llinás M, Pradel G. A seven-helix protein constitutes stress granules crucial for regulating translation during human-to-mosquito transmission of Plasmodium falciparum. PLoS Pathog. 2018 14(8):e1007249. PMID: 30133543
Other associated proteins
PFID | Formal Annotation |
---|---|
PF3D7_0525400 | G-protein coupled receptor, putative |
PF3D7_1224300 | polyadenylate-binding protein 1, putative |
PF3D7_1474900 | trailer hitch homolog, putative |