Left: Incubation of IRBCs with AlF reveals vesicle chains. (A-B) Ultrastructural characterization of glutaraldehyde-fixed trophozoite stage IRBCs revealed vesicles with an electron-dense limiting membrane arranged in chains in the RBC cytosol (black arrowhead) or (C) closely apposed to the erythrocyte plasma membrane. A typical Maurer cleft is observed (A; white arrowhead). (D) Immunoelectron microscopy confirmed the long, slender unit membranes in the RBC cytosol are Maurer clefts. MC indicates Maurer cleft; P, parasite; PVM, parasitophorous vacuolar membrane; PPM, parasite plasma membrane, RBCM, red blood cell membrane; and V, vesicles. Scale bar = 70 nm. Beck HP, Tilley L. Genesis of and trafficking to the Maurer's clefts of Plasmodium falciparum-infected erythrocytes. Mol Cell Biol. 2006
Other associated proteins
| PFID | Formal Annotation |
|---|---|
| PF3D7_0101300 | Pfmc-2TM Maurer's cleft two transmembrane protein |
| PF3D7_0221500 | Pfmc-2TM Maurer's cleft two transmembrane protein, pseudogene |
| PF3D7_0222100 | Pfmc-2TM Maurer's cleft two transmembrane protein |
| PF3D7_0223500 | erythrocyte membrane protein 1, PfEMP1 |
| PF3D7_0324100 | Pfmc-2TM Maurer's cleft two transmembrane protein |
| PF3D7_0416800 | small GTP-binding protein sar1 |
| PF3D7_0601200 | Pfmc-2TM Maurer's cleft two transmembrane protein |
| PF3D7_0631400 | Pfmc-2TM Maurer's cleft two transmembrane protein |
| PF3D7_0701600 | Pfmc-2TM Maurer's cleft two transmembrane protein |
| PF3D7_0713100 | Pfmc-2TM Maurer's cleft two transmembrane protein |
| PF3D7_1039700 | Pfmc-2TM Maurer's cleft two transmembrane protein |
| PF3D7_1100800 | Pfmc-2TM Maurer's cleft two transmembrane protein |
