Expression and localization of PfGAP40 in Plasmodium falciparum. Costaining of PfGAP40-Ty with PfGAP45 in ring (R), trophozoite (T), early schizont (ES), late schizont (LZ), free merozoite (MZ), and gametocyte (GC) of P. falciparum. PfGAP40-Ty colocalized with PfGAP45 and Pfs16 around the periphery of segmented schizonts, free merozoites, and gametocytes. In the merged color image, the PfGAP40-Ty signal is green, the antibody specific for the PfGAP45 or Pfs16 protein is red, and the parasite nuclei are stained with 4′,6-diamino-2-phenylindole (DAPI) in blue.
He L, Qiu Y, Pang G, Li S, Wang J, Feng Y, Chen L, Zhu L, Liu Y, Cui L, Cao Y, Zhu X. Plasmodium falciparum GAP40 Plays an Essential Role in Merozoite Invasion and Gametocytogenesis. Microbiol Spectr. 2023 e0143423. PMID: 37249423.
Other associated proteins
PFID | Formal Annotation |
---|---|
PF3D7_0406200 | parasitophorous vacuole membrane protein s16; sexual stage-specific protein s16 |
PF3D7_1222700 | glideosome-associated protein 45 |