Summary model of SEC14-GOLD protein functions. (A), Summary of various interactions with proteins, lipids or ligands, described for different parts of SEC14-GOLD proteins. (B), Model of AtPATL2, binding to phospholipids and interacting with transport protein in the plasma membrane, leading to prevention of oxidative stress and lipid peroxidation; PATL2 may exchange or present the antioxidant a-tocopherol. The cellular physiological effect may comprise vesicle formation and regulation of transporter abundance and activity. (C), Explanations of symbols used in (A, B). Montag K, Ivanov R, Bauer P. Role of SEC14-like phosphatidylinositol transfer proteins in membrane identity and dynamics. Front Plant Sci. 2023 14:1181031.