PF3D7_0627300 E3 ubiquitin-protein ligase RNF5, putative

Identification of putative Tail-Anchored (TA) proteins in P. falciparum 3D7 . IFA images showing regions of colocalization (arrowheads) between PfRNF5 (top and middle panels; green) in P. falciparum 3D7 or HA-PfSec61b transgenic parasites (bottom panel; red) with the ER marker PfBiP (red in the top and the middle panels; green in the bottom panel). Corresponding fluorescent and merged (with brightfield) images are as shown. Boxed areas (dotted outline) are magnified at the right. For all IFA images, scale bar, 5 μm; e, erythrocyte; p, parasite. Kumar T, Maitra S, Rahman A, Bhattacharjee S. A conserved guided entry of tail-anchored pathway is involved in the trafficking of a subset of membrane proteins in Plasmodium falciparum. PLoS Pathog. 2021 17(11):e1009595. PMID: 34780541

Other associated proteins

PFID Formal Annotation
PF3D7_0917900 PfHsp70-2
PF3D7_1346100 protein transport protein SEC61 subunit alpha
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