The localization of PfMC-2TM to Maurer’s clefts immediately after parasite invasion of red blood cell. (Left) Stage specific expression and localization of PfMC-2TM in P. falciparum 3D7 infected erythrocytes was visualized using SP1C1 (mAb) and co-localized with REX1 (green) specific antibodies. Infected red blood cells were percoll synchronized and collected 4, 8, 12, 16, 30, 42 and 51 h post invasion of merozoites. Expression of PfMC-2TM (red) and co-localization with REX1 (green). (B) Stage specific expression and localization of RhopH3 and SERA 1 using Anti-SERA1 and anti-RhopH3 antisera were used for endogenous expression controls. Yadavalli R, Peterson JW, Drazba JA, Sam-Yellowe TY. Trafficking and Association of Plasmodium falciparum MC-2TM with the Maurer's Clefts. Pathogens. 2021 10(4):431.