Upper: Localization of RhopH2 in the rhoptries of schizonts with polyclonal and monoclonal Abs.

Lower: Electron micrograph of a merozoite (M) reacted with the polyvalent antibodies against the 140 000 mol. wt. protein, followed by Protein A-gold label. Gold particles (arrow) bind specifically to electron dense rhoptries (R) (bar, 0.1 mm).

Holder AA, Freeman RR, Uni S, Aikawa M. Isolation of a Plasmodium falciparum rhoptry protein. Mol Biochem Parasitol. 1985 14:293-303.