PfMSPDBL1 and -2 localize to the merozoite surface. Immunofluorescence assays of late stage schizonts and merozoites were prepared from P. falciparum
(3D7 line) parasites probed with either rabbit or mouse polyclonal antibodies made to PfMSPDBL2 and marker proteins MSP119 (1st and 2nd rows), PfMSPDBL1 (3rd and 4th rows), or RON4 (5th row). 1st column, phase view; 2nd column, DAPI stained parasites; 3rd column, localization of PfMSPDBL2 (green); 4th column, localization of marker protein (red); 5th column, the merge of 3rd and 4th columns, and 6th column, the merge of columns 2–4.
Hodder AN, Czabotar PE, Uboldi AD, Clarke OB, Lin CS, Healer J, Smith BJ, Cowman AF. Insights into Duffy binding-like domains through the crystal structure and function of the merozoite surface protein MSPDBL2 from Plasmodium falciparum. J Biol Chem. 2012 287(39):32922-39.
Other associated proteins
PFID | Formal Annotation |
---|---|
PF3D7_1035700 | duffy binding-like merozoite surface protein |
PF3D7_1036300 | merozoite surface protein |
PF3D7_1116000 | rhoptry neck protein 4 |