PfDegP exists in a multimeric complex, and is associated with parasite proteins Hsp70 and Eno. Parasites were stained with anti-DegP and anti-Hsp70 (B) or anti-Eno (C) antiserum; parasite nuclei were stained with 4′,6-diamidino-2-phenylindole (DAPI). Fluorescence signals from DegP and Hsp70 or Eno antibodies showed significant merging, with a co-localization coefficient > 0.80.
Sharma S, Jadli M, Singh A, Arora K, Malhotra P. A secretory multifunctional serine protease, DegP of Plasmodium falciparum, plays an important role in thermo-oxidative stress, parasite growth and development. FEBS J. 2014 Mar;281(6):1679-99.
Other associated proteins
PFID | Formal Annotation |
---|---|
PF3D7_0807700 | serine protease DegP |
PF3D7_0818900 | PfHsp70-1 |