Comparison of PfSec12 localization with markers for the ER and Golgi. Parasites were co-transfected with plasmids for expression of mRFP–PfSec12 (from the native pfsec12 5′ UTR) with either (A) GFP–SDEL, a marker for the general ER, or (B) PfGRASP–GFP, a cis-Golgi marker. mRFP–PfSec12 was localized throughout the ER coincident with GFP–SDEL, in close apposition to PfGRASP-labelled Golgi. Bar μm. Lee MC, Moura PA, Miller EA, Fidock DA. Plasmodium falciparum Sec24 marks transitional ER that exports a model cargo via a diacidic motif. Mol Microbiol. 2008. PMID: 18410493
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PubMed Article: Plasmodium falciparum Sec24 marks transitional ER that exports a model cargo via a diacidic motif
Other associated proteins
PFID | Formal Annotation |
---|---|
PF3D7_1116400 | guanine nucleotide-exchange factor SEC12 |