Immunoelectron micrographs. (A) Section of an early schizont of P.falciparum (Brazilian strain 7G8, drug sensitive) incubated with anti-CaM antibody and protein A-gold. Gold particles (arrows) are scattered diffusely over the schizont (S) cytoplasm. Little label is associated with the host erythrocyte (RBC). (x43,000.) (B) Section of merozoite. Gold particles indicate the location of CaM at the apical end (A) and the ductule of rhoptries (R). (x52,000.)

Scheibel LW, Colombani PM, Hess AD, Aikawa M, Atkinson CT, Milhous WK. Calcium and calmodulin antagonists inhibit human malaria parasites (Plasmodium falciparum): implications for drug design. Proc Natl Acad Sci U S A. 1987 84:7310-4.