Complex formation of 7-Helix-1 with Puf2 and repressed pfs25 mRNA and Pfs25 synthesis. Expression of Pfs25 and Pfs230 in activated gametocytes. WT NF54 and 7-Helix-1-KO 2E6 gametocytes at 30 min p.a. were immunolabeled with rabbit anti-Pfs25 (green) and mouse anti-Pfs230 antibodies (red). Nuclei were highlighted by Hoechst33342 nuclear stain (blue). Bar, 5 μm. Bennink S, von Bohl A, Ngwa CJ, Henschel L, Kuehn A, Pilch N, Weißbach T, Rosinski AN, Scheuermayer M, Repnik U, Przyborski JM, Minns AM, Orchard LM, Griffiths G, Lindner SE, Llinás M, Pradel G. A seven-helix protein constitutes stress granules crucial for regulating translation during human-to-mosquito transmission of Plasmodium falciparum. PLoS Pathog. 2018 14(8):e1007249. PMID: 30133543;