PfnPrx is a nuclear protein. Top) Immuno-fluorescence using the mouse monoclonal anti-PfnPrx antibody demonstrates localisation of PfnPrx in the nucleus throughout the erythrocytic stage. Bottom) PfnPrx does not localise to the tight junction of merozoites in the process of invasion. Immunofluorescence with mouse monoclonal anti-nPrx and rabbit anti-RON4 antibody shows that PfnPrx is restricted to the nucleus in parasites invading a red blood cell.
Richard D, Bartfai R, Volz J, Ralph SA, Muller S, Stunnenberg HG, Cowman AF. A genome-wide chromatin-associated nuclear from the malaria parasite Plasmodium falciparum. J Biol Chem. 2011 286(13):11746-55
PubMed Article: A genome-wide chromatin-associated nuclear peroxiredoxin from the malaria parasite Plasmodium falciparum
Other associated proteins
PFID | Formal Annotation |
---|---|
PF3D7_1027300 | peroxiredoxin merozoite capping protein 1 |